Now showing items 1-2 of 2

    • A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis 

      Gayán, Javier; González-Pérez, Antonio; Bermudo, Fernando; Eugenia Sáez, María; Royo Sánchez-Palencia, José Luis; Quintas, Antonio; Galan, José J.; Morón, Francisco J.; Ramirez Lorca, Reposo; Real, Luis M.; Ruiz González, Agustín (BioMed Central, 2008)
      Background: The difficulty in elucidating the genetic basis of complex diseases roots in the many factors that can affect the development of a disease. Some of these genetic effects may interact in complex ways, proving ...
    • Methylation alterations are not a major cause of PTTG1 missregulation 

      Hidalgo, Manuel; Galan, Jose J.; Sáez, Carmen; Ferrero, Eduardo; Castilla, Carolina; Ramirez Lorca, Reposo; Pelaez, Pablo; Ruiz, Agustín; Japón, Miguel A.; Royo Sánchez-Palencia, José Luis (BioMed Central, 2008)
      Background: On its physiological cellular context, PTTG1 controls sister chromatid segregation during mitosis. Within its crosstalk to the cellular arrest machinery, relies a checkpoint of integrity for which gained the ...