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    • A scaffold protein that chaperones a cysteine-sulfenic acid in H2O2 signaling 

      Bersweiler, Antoine; d’Autréaux, Benoît; Mazon, Hortense; Kriznik, Alexandre; Bellí i Martínez, Gemma; Delaunay-Moisan, Agnès; Toledano, Michel B.; Rahuel-Clermont, Sophie (Nature Reseach, 2017)
      In Saccharomyces cerevisiae, Yap1 regulates an H2O2-inducible transcriptional response that controls cellular H2O2 homeostasis. H2O2 activates Yap1 by oxidation through the intermediacy of the thiol-peroxidase Orp1. Upon ...