Now showing items 1-2 of 2

    • A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis 

      Gayán, Javier; González-Pérez, Antonio; Bermudo, Fernando; Eugenia Sáez, María; Royo Sánchez-Palencia, José Luis; Quintas, Antonio; Galan, José J.; Morón, Francisco J.; Ramirez Lorca, Reposo; Real, Luis M.; Ruiz González, Agustín (BioMed Central, 2008)
      Background: The difficulty in elucidating the genetic basis of complex diseases roots in the many factors that can affect the development of a disease. Some of these genetic effects may interact in complex ways, proving ...
    • Genetic structure of the Spanish population 

      Gayán, Javier; Galan, José J.; González-Pérez, Antonio; Sáez, María Eugenia; Martínez-Larrad, María Teresa; Zabena, Carina; Rivero, M. Carmen; Salinas, Ana; Ramírez-Lorca, Reposo; Morón, Francisco J.; Royo Sánchez-Palencia, José Luis; Moreno-Rey, Concha; Velasco, Juan; Carrasco, José M.; Molero, Eva; Ochoa, Carolina; Ochoa, María Dolores; Gutiérrez, Marta; Reina, Mercedes; Pascual, Rocío; Romo-Astorga, Alejandro; Susillo-González, Juan Luis; Vázquez, Enrique; Real, Luis M.; Ruiz, Agustín; Serrano-Ríos, Manuel (BioMed Central, 2010-05-25)
      Background Genetic admixture is a common caveat for genetic association analysis. Therefore, it is important to characterize the genetic structure of the population under study to control for this kind of potential bias. ...