Now showing items 169-188 of 548

    • Effects of Ethnicity on the Prevalence of Obstructive Sleep Apnoea in Patients with Acute Coronary Syndrome: A Pooled Analysis of the ISAACC Trial and Sleep and Stent Study. 

      Koo, Chieh-Yang; Sánchez de la Torre, Alicia; Loo, Germaine; Sánchez de la Torre, Manuel; Zhang, Junjie; Durán-Cantolla, Joaquín; Li, Ruogu; Mayós Pérez, Mercè; Sethi, Rithi; Abad, Jorge; Drager, Luciano; Coloma, Ramón; Hein, Thet; Ho, Hee-Hwa; Jim, Man-Hong; Ong, Thun-How; Tai, Bee-Choo; Aldomá, Albina; Lee, Chi-Hang; Barbé Illa, Ferran (ElsevierAustralian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS)Cardiac Society of Australia and New Zealand (CSANZ), 2017)
      Objective: Obstructive sleep apnea (OSA) is an increasing yet under-recognized risk factor for acute coronary syndrome (ACS). We sought to determine the effects of ethnicity on the prevalence of OSA in patients presenting ...
    • Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients 

      de Haro, Candelaria; Magrans, Rudys; López-Aguilar, Josefina; Montanyà, Jaume; Lena, Enrico; Subirà, Carles; Fernández‑Gonzalo, Sol; Gomà Fernández, Gemma; Fernández, Rafael; Albaiceta, Guillermo M.; Skrobik, Yoanna; Lucangelo, Umberto; Murias, Gastón; Ochagavia, Ana; Kacmarek, Robert M.; Rué i Monné, Montserrat; Blanch, Lluís (BMC (part of Springer Nature), 2019)
      BACKGROUND: In critically ill patients, poor patient-ventilator interaction may worsen outcomes. Although sedatives are often administered to improve comfort and facilitate ventilation, they can be deleterious. Whether ...
    • El aborto legal en Colombia: opiniones de un grupo de estudiantes de Enfermería 

      Laza-Vásquez, Celmira; Cerquera-Gallego, Eric Yamid; Ferrer-Pérez, Tania Alejandra; Gutiérrez-Ocampos, Yessenia (Universidad de Antioquia, 2019-01-31)
      Introducción: En el año 2006, el Estado colombiano legalizó el aborto en tres situaciones específicas, mediante la Sentencia C-355, marcando un hito importante en una sociedad impregnada por fuertes valores patriarcales. ...
    • El cuidado de los niños(as) con el síndrome congénito de Zika en Colombia: consecuencias en la vida de las mujeres 

      Laza-Vásquez, Celmira; Castaño-Paya, Paola Andrea; Sinisterra-Castro, Juan Pablo; Gea Sánchez, Montserrat; Briones Vozmediano, Erica Tula (Elsevier, 2021-02-15)
    • El Movimiento social del cáncer de mama como dispositivo neoliberal 

      Laza-Vásquez, Celmira (Universidade Federal de Santa Catarina, 2017-10-23)
      Son varios los investigadores que se han ocupado del estudio de los movimientos sociales, sin embargo, hay unos movimientos sociales que de cierta forma han sido 'invisiblizados' por las Ciencias Sociales, los Movimientos ...
    • Empathy and burnout of emergency professionals of a health region: a cross-sectional study 

      Yuguero Torres, Oriol; Forné Izquierdo, Carles; Esquerda i Aresté, Montse; Pifarré Paredero, Josep; Abadías, María José; Viñas Salas, Joan (Lippincott Williams & Wilkins, 2017)
      The objective of this study is to assess the association between levels of empathy and burnout of emergency professionals in all the assistance levels. A cross-sectional observational study was conducted in the health ...
    • ENDOG Impacts on Tumor Cell Proliferation and Tumor Prognosis in the Context of PI3K/PTEN Pathway Status 

      Barés Junqué, Gisel; Beà Tàrrega, Aida; Hernández, Luís; Navaridas Fernández de Bobadilla, Raúl; Felip, Isidre; Megino-Luque, Cristina; Blasco Angulo, Natividad; Nadeu, Ferran; Campo, Elías; Llovera i Tomàs, Marta; Dolcet Roca, Xavier; Sanchis, Daniel (MDPI, 2021)
      EndoG influences mitochondrial DNA replication and is involved in somatic cell proliferation. Here, we investigated the effect of ENDOG/Endog expression on proliferation in different tumor models. Noteworthy, ENDOG ...
    • EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes 

      Zhang, Jisheng; Ye, Junmei; Altafaj, Albert; Cardona Colom, Maria; Bahi i Pla, Núria; Llovera i Tomàs, Marta; Cañas, Xavier; Cook, Stuart A.; Comella i Carnicé, Joan Xavier; Sanchis, Daniel (Public Library of Science (PLoS), 2011)
      Mitochondrial dysfunction, caspase activation and caspase-dependent DNA fragmentation are involved in cell damage in many tissues. However, differentiated cardiomyocytes repress the expression of the canonical apoptotic ...
    • Endogenous controls and microRNA profile in female patients with obstructive sleep apnea 

      Zapater, Andrea; Benítez, Iván; Santamaria-Martos, Fernando; Pinilla, Lucía; Targa, Adriano; de Gonzalo Calvo, David; Torres, Gerard; Minguez Roure, Olga; Cortijo, Anunciación; Dalmases, Mireia; Barbé Illa, Ferran; Sánchez de la Torre, Manuel (Nature Research, 2022)
      This work was supported by Instituto de Salud Carlos III (PI14/01266, PI18/00449, PI19/00907, PI20/00577), co-funded by FEDER, “Una manera de hacer europa”, IRBLleida – Fundació Dr. Pifarré, CERCA Programme/Generalitat de ...
    • Endometrial Carcinoma Diagnosis: Use of FIGO Grading and Genomic Subcategories in Clinical Practice: Recommendations of the International Society of Gynecological Pathologists 

      Soslow, Robert A.; Tornos, Carmen; Park, Kay J.; Malpica, Anais; Matias-Guiu, Xavier; Oliva, Esther; Parkash, Vinita; Carlson, Joseph A.; McCluggage, W. Glenn; Gilks, C. Blake (Lippincott, Williams & Wilkins, 2019)
      In this review, we sought to address 2 important issues in the diagnosis of endometrial carcinoma: how to grade endometrial endometrioid carcinomas and how to incorporate the 4 genomic subcategories of endometrial carcinoma, ...
    • Endometrial Carcinoma, Grossing and Processing Issues: Recommendations of the International Society of Gynecologic Pathologists 

      Malpica, Anais; Euscher, Elizabeth; Hecht, Jonathan; Ali-Fehmi, Rouba; Quick, Charles; Singh, Naveena; Horn, Lars-Christian; Alvarado-Cabrero, Isabel; Matias-Guiu, Xavier; Hirschowitz, Lynn; Duggan, Máire; Ordi, Jaume; Parkash, Vinita; Mikami, Yoshiki; Quddus, M. Ruhul; Zaino, Richard; Staebler, Annette; Zaloudek, Charles; McCluggage, W. Glenn; Oliva, Esther (Lippincott, Williams & Wilkins, 2019)
      Endometrial cancer is the most common gynecologic neoplasm in developed countries; however, updated universal guidelines are currently not available to handle specimens obtained during the surgical treatment of patients ...
    • Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation 

      Eritja Sánchez, Núria; Navaridas Fernández de Bobadilla, Raúl; Ruiz Mitjana,Anna; Vidal Sabanés, Maria; Egea Navarro, Joaquim; Encinas Martín, Mario; Matias-Guiu, Xavier; Dolcet Roca, Xavier (MDPI, 2021-10-05)
      TGF-β has a dichotomous function, acting as tumor suppressor in premalignant cells but as a tumor promoter for cancerous cells. These contradictory functions of TGF-β are caused by different cellular contexts, including ...
    • Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function 

      McDermott Roe, Chris; Ye, Junmei; Ahmed, Rizwan; Sun, Xi-Ming; Serafín, Anna; Ware, James; Bottolo, Leonardo; Muckett, Phil; Cañas, Xavier; Zhang, Jisheng; Rowe, Glenn C.; Buchan, Rachel; Lu, Han; Braithwaite, Adam; Mancini, Massimiliano; Hauton, David; Martí, Ramón; García Arumí, Elena; Hubner, Norbert; Jacob, Howard; Serikawa, Tadao; Zidek, Vaclav; Papousek, Frantisek; Kolar, Frantisek; Cardona Colom, Maria; Ruiz Meana, Marisol; García Dorado, David; Comella i Carnicé, Joan Xavier; Felkin, Leanne E.; Barton, Paul J. R.; Zoltan Arany; Pravenec, Michal; Petretto, Enrico; Sanchis, Daniel; Cook, Stuart A. (Macmillan Publishers Limited, 2011)
      Left ventricular mass (LVM) is a highly heritable trait1 and an independent risk factor for all-cause mortality2. So far, genome-wide association studies have not identified the genetic factors that underlie LVM variation3, ...
    • Engineered Trx2p industrial yeast strain protects glycolysis and fermentation proteins from oxidative carbonylation during biomass propagation 

      Gómez-Pastor, Rocío; Pérez-Torrado, Roberto; Cabiscol Català, Elisa; Ros Salvador, Joaquim; Matallana, Emilia (BioMed Central, 2012)
      Background: In the yeast biomass production process, protein carbonylation has severe adverse effects since it diminishes biomass yield and profitability of industrial production plants. However, this significant detriment ...
    • Enhanced synaptic plasticity and spatial memory in female but not male FLRT2-haplodeficient mice 

      Cicvaric, Ana; Yang, Jiaye; Bulat, Tanja; Zambon, Alice; Dominguez-Rodriguez, Manuel; Kühn, Rebekka; Sadowicz, Michael G.; Siwert, Anjana; Egea Navarro, Joaquim; Pollak, Daniela D.; Moeslinger, Thomas; Monje, Francisco J. (Nature Publishing Group, 2018)
      The Fibronectin Leucine-Rich Transmembrane protein 2 (FLRT2) has been implicated in several hormone -and sex-dependent physiological and pathological processes (including chondrogenesis, menarche and breast cancer); is ...
    • EphA4-Dependent Axon Guidance Is Mediated by the RacGAP a2-Chimaerin 

      Wegmeyer, Heike; Egea Navarro, Joaquim; Rabe, Nadine; Gezelius, Henrik; Filosa, Alessandro; Enjin, Anders; Varoqueaux, Frederique; Deininger, Katrin; Schnütgen, Frank; Brose, Nils; Klein, Rüdiger; Kullander, Klas; Betz, Andrea (Elsevier, 2007)
      Neuronal network formation in the developing nervous system is dependent on the accurate navigation of nerve cell axons and dendrites, which is controlled by attractive and repulsive guidance cues. Ephrins and their ...
    • Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis 

      Moran, Sebastian; Martínez Cardús, Anna; Sayols, Sergi; Musulén, Eva; Balañá, Carme; Estival Gonzalez, Anna; Moutinho, Cátia; Heyn, Holger; Diaz Lagares, Angel; Castro de Moura, Manuel; Stella, Giulia M.; Comoglio, Paolo M.; Ruiz Miró, Maria; Pazo Cid, Roberto; Antón, Antonio; Lopez Lopez, Rafael; Soler, Gemma; Longo, Federico; Guerra, Isabel; Fernandez, Sara; Assenov, Yassen; Plass, Christoph; Morales, Rafael; Carles, Joan; Bowtell, David; Mileshkin, Linda; Sia, Daniela; Tothill, Richard; Tabernero, Josep; Llovet, Josep M.; Esteller, Manel; Matias-Guiu, Xavier (Elsevier, 2016)
      Cancer of unknown primary ranks in the top ten cancer presentations and has an extremely poor prognosis. Identification of the primary tumour and development of a tailored site-specific therapy could improve the survival ...
    • ER alpha-mediated repression of pro-inflammatory cytokine expression by glucocorticoids reveals a crucial role for TNF alpha and IL1 alpha in lumen formation and maintenance 

      Eritja Sánchez, Núria; Mirantes Barbeito, Cristina; Llobet Navàs, David; Masip Vilà, Gemma; Matias-Guiu, Xavier; Dolcet Roca, Xavier (Company of Biologists Ltd., 2013)
      Most glandular tissues comprise polarized epithelial cells organized around a single central lumen. Although there is active research investigating the molecular networks involved in the regulation of lumenogenesis, little ...
    • Erectile dysfunction in obstructive sleep apnea patients: A randomized trial on the effects of Continuous Positive Airway Pressure (CPAP) 

      Pascual, Mercè; Batlle Garcia, Jordi de; Barbé Illa, Ferran; Castro-Grattoni, Anabel L.; Auguet, Josep M.; Pascual, Lydia; Vilà, Manel; Cortijo, Anunciación; Sánchez de la Torre, Manuel (Public Library of Science, 2018)
      Objectives Obstructive sleep apnea (OSA) is among the least studied risk factors for erectile dysfunction (ED). We aimed to determine ED prevalence in newly-diagnosed OSA patients, describe their main characteristics ...
    • Erk1/2 activation in stromal fibroblasts from sporadic basal cell carcinomas 

      Aguayo Ortiz, Rafael; Rafel i Borrell, Marta; Santacana Espasa, Maria; Pérez Fusté, Noel; Garí Marsol, Eloi (American Society for Dermatologic Surgery, 2015)
      BACKGROUND Constitutive activation of the Erk pathway can lead to oncogenic transformation. However, the Erk pathway is not activated in human basal cell carcinomas (BCCs); although in animal models, this seems to be ...