Recent Submissions

  • Factor structure of the Maslach Burnout Inventory Human Services Survey in Spanish urgency healthcare personnel: a cross-sectional study 

    Forné Izquierdo, Carles; Yuguero Torres, Oriol (Springer Nature, 2022)
    Background: The Maslach Burnout Inventory (MBI) is an instrument commonly used to evaluate burnout syndrome. The goal of the present study was to assess the internal reliability and the performance of the items and the ...
  • A mathematical model for strigolactone biosynthesis in plants 

    Lucido, Abel; Basallo, Oriol; Sorribas Tello, Albert; Marin-Sanguino, Alberto; Vilaprinyo Terré, Ester; Alves, Rui (Frontiers Media, 2022)
    Strigolactones mediate plant development, trigger symbiosis with arbuscular mycorrhizal fungi, are abundant in 80% of the plant kingdom and help plants gain resistance to environmental stressors. They also induce ...
  • Genome-wide transcriptional profiling of pulmonary functional sequelae in ARDS- secondary to SARS-CoV-2 infection 

    García Hidalgo, María Coronada; Peláez, Rafael; González, Jessica; Santisteve, Sally; Benítez, Iván; Molinero, Marta; Perez-Pons, Manel; Belmonte, Thalía; Torres, Gerard; Moncusí Moix, Anna; Gort Paniello, Clara; Aguilà, Maria; Seck, Faty; Carmona, Paola; Caballero, Jesús; Barberà, Carme; Ceccato, Adrián; Fernández Barat, Laia; Ferrer, Ricard; Garcia-Gasulla, Dario; Lorente, José Ángel; Menéndez, Rosario; Motos, Anna; Peñuelas, Oscar; Riera, Jordi; Bermejo Martin, Jesús F.; Torres, Antoni; Barbé Illa, Ferran; de Gonzalo Calvo, David; Larrayoz, Ignacio M. (Elsevier, 2022)
    Background: Up to 80% of patients surviving acute respiratory distress syndrome (ARDS) secondary to SARS-CoV- 2 infection present persistent anomalies in pulmonary function after hospital discharge. There is a limited ...
  • Ocular Surface plasmacytoma 

    Domínguez Bernaus, Marta; Cid-Bertomeu, Pau; Vilardell, Felip; Huerva, Valentín (European Society of Medicine., 2022)
    Conjunctival plasmacytomas are rare tumours that may be solitary or related with multiple myeloma (MM), a malignant systemic plasma cell neoplasm that tends to metastasize. Plasma cell infiltration of bone ...
  • The ERK5/NF‑κB signaling pathway targets endometrial cancer proliferation and survival 

    Diéguez‑Martínez, Nora; Espinosa‑Gil, Sergio; Yoldi, Guillermo; Gorgisen, Gokhan; Domingo Ortí, Inés; Viñas Casas, Maria; Bolinaga Ayala, Idoia; Megías Roda, Elisabet; Pérez‑Montoyo, Héctor; José Ramón, Bayascas Ramírez; Colás, Eva; Dolcet Roca, Xavier; Lizcano, José M. (Springer Science, 2022)
    Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy regimens, overall survival of patients with high-risk EC tumors is ...
  • Feasibility and Acceptability of Personalized Breast Cancer Screening (DECIDO Study): A Single-Arm Proof-of-Concept Trial 

    Laza-Vásquez, Celmira; Martínez Alonso, Montserrat; Forné Izquierdo, Carles; Vilaplana Mayoral, Jordi; Cruz Esteve, María Inés; Sánchez-López, Isabel; Reñé Reñé, Mercè; Cazorla, Cristina; Hernández Andreu, Marta; Galindo Ortego, Gisela; Llorens Gabandé, Montserrat; Pons Rodríguez, Anna; Rué i Monné, Montserrat; DECIDO Group (MDPI, 2022-08)
    The aim of this study was to assess the acceptability and feasibility of offering risk-based breast cancer screening and its integration into regular clinical practice. A single-arm proof-of-concept trial was conducted ...
  • ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma 

    Concin, Nicole; Matias-Guiu, Xavier; Vergote, Ignace; Cibula, David; Raza Mirza, Mansoor; Marnitz, Simone; Ledermann, Jonathan; Bosse, Tjalling; Chargari, Cyrus; Fagotti, Anna; Fotopoulou, Christina; Gonzalez Martin, Antonio; Lax, Sigurd; Lorusso, Domenica; Marth, Christian; Morice, Philippe; Nout, Remi; O'Donnell, Dearbhaile; Querleu, Denis; Raspollini, Maria Rosaria; Sehouli, Jalid; Sturdza, Alina; Taylor, Alexandra; Westermann, Anneke; Wimberger, Pauline; Colombo, Nicoletta; Planchamp, François; Creutzberg, Carien (BMJ, 2021)
    A European consensus conference on endometrial carcinoma was held in 2014 to produce multi-disciplinary evidence-based guidelines on selected questions. Given the large body of literature on the management of endometrial ...
  • Bulk autophagy induction and life extension is achieved when iron is the only limited nutrient in Saccharomyces cerevisiae 

    Montellá-Manuel, Sandra; Pujol Carrión, Núria; Mechoud, Mónica A.; Torre Ruiz, M. A. de la (Portland Press; Biochemical Society, 2021)
    We have investigated the effects that iron limitation provokes in Saccharomyces cerevisiae exponential cultures. We have demonstrated that one primary response is the induction of bulk autophagy mediated by TORC1. Coherently, ...
  • A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes 

    Altés, Gisela; Vaquero, Marta; Cuesta, Sara; Anerillas Aljama, Carlos; Macià Armengol, Anna; Espinet Mestre, Carme; Ribera i Calvet, Joan; Bellusci, Saverio; Klein, Ophir D.; Yeramian Hakim, Andree; Dolcet Roca, Xavier; Egea Navarro, Joaquim; Encinas Martín, Mario (Springer, 2022)
    The Wolffian ducts (WD) are paired epithelial tubules central to the development of the mammalian genitourinary tract. Outgrowths from the WD known as the ureteric buds (UB) generate the collecting ducts of the kidney. ...
  • Identification of NHLRC1 as a Novel AKT Activator from a Lung Cancer Epigenome-Wide Association Study (EWAS) 

    Faltus, Christian; Lahnsteiner, Angelika; Barrdahl, Myrto; Assenov, Yassen; Hüsing, Anika; Bogatyrova, Olga; Laplana Lafaja, Marina; Johnson, Theron; Muley, Thomas; Meister, Michael; Warth, Arne; Thomas, Michael; Plass, Christoph; Kaaks, Rudolf; Risch, Angela (MDPI, 2022)
    Changes in DNA methylation identified by epigenome-wide association studies (EWAS) have been recently linked to increased lung cancer risk. However, the cellular effects of these differentially methylated positions (DMPs) ...
  • Metabolic engineering of Halomonas elongata: Ectoine secretion is increased by demand and supply driven approaches 

    Hobmeier, Karina; Oppermann, Martin; Stasinski, Natalie; Kremling, Andreas; Pflüger Grau, Katharina; Kunte, Hans Jörg; Marin-Sanguino, Alberto (Frontiers Media, 2022)
    The application of naturally-derived biomolecules in everyday products, replacing conventional synthetic manufacturing, is an ever-increasing market. An example of this is the compatible solute ectoine, which is contained ...
  • Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition 

    Ruiz Mitjana, Anna; Navaridas Fernández de Bobadilla, Raúl; Vidal Sabanés, Maria; Perramon Güell, Aida; Yeramian Hakim, Andree; Felip Nogués, Isidre; Eritja Sánchez, Núria; Egea Navarro, Joaquim; Encinas Martín, Mario; Matias-Guiu, Xavier; Dolcet Roca, Xavier (Nature Research, 2022)
    The extracellular matrix and the correct establishment of epithelial cell polarity plays a critical role in epithelial cell homeostasis and cell polarity. In addition, loss of tissue structure is a hallmark of carcinogenesis. ...
  • One Year Overview and Follow-Up in a Post-COVID Consultation of Critically Ill Patients 

    González, Jessica; Zuil, María; Benítez, Iván; de Gonzalo Calvo, David; Aguilar, María; Santisteve, Sally; Vaca, Rafaela; Minguez Roure, Olga; Seck, Faty; Torres, Gerard; Batlle Garcia, Jordi de; Gómez Falguera, Silvia; Barril, Silvia; Moncusí Moix, Anna; Monge Esqué, Aida; Gort Paniello, Clara; Ferrer, Ricard; Ceccato, Adrián; Fernández Barat, Laia; Motos, Anna; Riera, Jordi; Menéndez, Rosario; García Gasulla, Dario; Peñuelas, Oscar; Labarca, Gonzalo; Caballero, Jesús; Barberà, Carme; Torres, Antoni; Barbé Illa, Ferran (Frontiers Media, 2022)
    The long-term clinical management and evolution of a cohort of critical COVID-19 survivors have not been described in detail. We report a prospective observational study of COVID-19 patients admitted to the ICU between ...
  • Antitumor Effects of Ral-GTPases Downregulation in Glioblastoma. 

    Cemeli, Tània; Guasch Vallés, Marta; Ribes Santolaria, Marina; Ibars Estiarte, Eva Irene; Navaridas Fernández de Bobadilla, Raúl; Dolcet Roca, Xavier; Pedraza González, Neus; Colomina i Gabarrella, Neus; Torres Rosell, Jordi; Ferrezuelo, Francisco; Herreros Danés, Judit; Garí Marsol, Eloi (MDPI, 2022-07-29)
    Glioblastoma (GBM) is the most common tumor in the central nervous system in adults. This neoplasia shows a high capacity of growth and spreading to the surrounding brain tissue, hindering its complete surgical resection. ...
  • Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome 

    Zapater, Andrea; Solelhac, Geoffroy; Sánchez de la Torre, Alicia; Gracia-Lavedan, Esther; Benítez, Iván; Torres, Gerard; Batlle Garcia, Jordi de; Haba Rubio, José; Berger, Mathieu; Abad, Jorge; Durán-Cantolla, Joaquín; Urrutia, Amaia; Mediano, Olga; Masdeu, María José; Ordax-Carbajo, Estrella; Masa, Juan Fernando; Peña, Mónica de la; Mayós Pérez, Mercè; Coloma, Ramón; Montserrat, Josep Maria; Chiner, Eusebi; Minguez Roure, Olga; Pascual, Lydia; Cortijo, Anunciación; Martínez, Dolores; Dalmases, Mireia; Lee, Chi-Hang; McEvoy, R. Doug; Barbé Illa, Ferran; Heinzer, Raphael; Sánchez de la Torre, Manuel (Frontiers Media, 2022)
    Introduction: Obstructive sleep apnea (OSA) severity is based on the apnea-hypopnea index (AHI). The AHI is a simplistic measure that is inadequate for capturing disease severity and its consequences in cardiovascular ...
  • Editorial: Molecular and Cellular Crosstalk on Neuronal Functionality and Regulation, From Development to Pathology 

    Segura, Inmaculada; Egea Navarro, Joaquim (Frontiers Media, 2022)
    EDITORIAL article
  • CAM Models: Lessons and Implications for CAM Evolution 

    Burgos, Asdrubal; Miranda, Enoc; Vilaprinyo Terré, Ester; Meza Canales, Iván David; Alves, Rui (Frontiers Media, 2022)
    The evolution of Crassulacean acid metabolism (CAM) by plants has been one of the most successful strategies in response to aridity. On the onset of climate change, expanding the use of water efficient crops and engineering ...
  • Accumulation of misfolded SOD1 outlines distinct patterns of motor neuron pathology and death during disease progression in a SOD1G93A mouse model of amyotrophic lateral sclerosis 

    Salvany, Sara; Casanovas i Llorens, Anna; Piedrafita Llorens, Lídia; Gras Artells, Sílvia; Calderó i Pardo, Jordi; Esquerda Colell, Josep (Wiley Open Access, 2022)
    Early misfolded superoxide dismutase 1 (mfSOD1) accumulation, motor neuron (MN) degeneration, and microgliosis are hallmark pathological features in SOD1G93A amyotrophic lateral sclerosis (ALS) mice. Because of the different ...
  • Psychometric Validation of the Cardiff Wound Impact Schedule Questionnaire in a Spanish Population with Diabetic Foot Ulcer 

    Granado Casas, Minerva; Martínez González, María Dolores; Martínez Alonso, Montserrat; Dòria, Montserrat; Alcubierre Calvo, Núria; Valls, Joan; Julve, Josep; Verdú-Soriano, José; Mauricio Puente, Dídac (MDPI, 2021)
    Diabetic foot ulcers (DFU) negatively affect the quality of life (QoL) of people with diabetes. The Cardiff Wound Impact Schedule (CWIS) questionnaire has been designed to measure the QoL of people with chronic foot wounds. ...
  • A Simple Scoring System to Differentiate Bacterial from Viral Infections in Acute Exacerbations of COPD Requiring Hospitalization 

    Ruiz González, Agustín; Sáez Huerta, Eduardo; Martínez Alonso, Montserrat; Bernet Sánchez, Albert; Porcel Pérez, José Manuel (Dove Press, 2022)
    Objective: Both bacteria and viruses may cause acute exacerbations of chronic obstructive pulmonary disease (AECOPD). The objective of this study was to identify readily available clinical parameters to discriminate between ...

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