Browsing Articles publicats (Informàtica i Enginyeria Industrial) by Author "Orobitg Cortada, Miquel"
Now showing items 1-5 of 5
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Cloud-Coffee: implementation of a parallel consistency-based multiple alignment algorithm in the T-Coffee package and its benchmarking on the Amazon Elastic-Cloud
Di Tommaso, Paolo; Orobitg Cortada, Miquel; Guirado Fernández, Fernando; Cores Prado, Fernando; Espinosa, Toni; Notredame, Cedric (Oxford University Press, 2010)Summary: We present the first parallel implementation of the T-Coffee consistency-based multiple aligner. We benchmark it on the Amazon Elastic Cloud (EC2) and show that the parallelization procedure is reasonably ... -
Exploiting parallelism on progressive alignment methods
Orobitg Cortada, Miquel; Guirado Fernández, Fernando; Notredame, Cedric; Cores Prado, Fernando (Springer Verlag, 2011)Multiple Sequence Alignment (MSA) constitutes an extremely powerful tool for important biological applications such as phylogenetic analysis, identification of conserved motifs and domains and structure prediction. In ... -
High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools
Orobitg Cortada, Miquel; Guirado Fernández, Fernando; Cores Prado, Fernando; Lladós Segura, Jordi; Notredame, Cedric (Elsevier, 2014-10-08)Multiple Sequence Alignment (MSA) is essential for a wide range of applications in Bioinformatics. Traditionally, the alignment accuracy was the main metric used to evaluate the goodness of MSA tools. However, with the ... -
Improving multiple sequence alignment biological accuracy through genetic algorithms
Orobitg Cortada, Miquel; Cores Prado, Fernando; Guirado Fernández, Fernando; Roig Mateu, Concepció; Notredame, Cedric (Springer, 2013)Accuracy on multiple sequence alignments (MSA) is of great significance for such important biological applications as evolution and phylogenetic analysis, homology and domain structure prediction. In such analyses, alignment ... -
T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension
Di Tommaso, Paolo; Moretti, Sebastien; Xenarios, Ioannis; Orobitg Cortada, Miquel; Montañola Lacort, Alberto (Oxford University Press, 2011)This article introduces a new interface for T-Coffee, a consistency-based multiple sequence alignment program. This interface provides an easy and intuitive access to the most popular functionality of the package. These ...