Now showing items 1-6 of 6

    • Accurate consistency-based MSA reducing the memory footprint 

      Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando; Lérida Monsó, Josep Lluís (Elsevier, 2021)
      Background and Objective: The emergence of Next-Generation sequencing has created a push for faster and more accurate multiple sequence alignment tools. The growing number of sequences and their longer sizes, which require ...
    • High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools 

      Orobitg Cortada, Miquel; Guirado Fernández, Fernando; Cores Prado, Fernando; Lladós Segura, Jordi; Notredame, Cedric (Elsevier, 2014-10-08)
      Multiple Sequence Alignment (MSA) is essential for a wide range of applications in Bioinformatics. Traditionally, the alignment accuracy was the main metric used to evaluate the goodness of MSA tools. However, with the ...
    • Optimization of Consistency-Based Multiple Sequence Alignment using Big Data technologies 

      Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando (Springer, 2019)
      With the advent of new high-throughput next-generation sequencing technologies, the volume of genetic data processed has increased significantly. It is becoming essential for these applications to achieve large-scale alignments ...
    • PPCAS: Implementation of a Probabilistic Pairwise Model for Consistency-Based Multiple Alignment in Apache Spark 

      Lladós Segura, Jordi; Guirado Fernández, Fernando; Cores Prado, Fernando (Springer, 2017)
      Large-scale data processing techniques, currently known as Big-Data, are used to manage the huge amount of data that are generated by sequencers. Although these techniques have significant advantages, few biological ...
    • Recovering accuracy methods for scalable consistency library 

      Lladós Segura, Jordi; Guirado Fernández, Fernando; Cores Prado, Fernando; Lérida Monsó, Josep Lluís; Notredame, Cedric (Springer Verlag, 2015-05-01)
      Multiple sequence alignment (MSA) is crucial for high-throughput next generation sequencing applications. Large-scale alignments with thousands of sequences are necessary for these applications. However, the quality of the ...
    • Scalable Consistency in T-Coffee Through Apache Spark and Cassandra Database 

      Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando (Mary Ann Liebert, 2018)
      Next-generation sequencing, also known as high-throughput sequencing, has increased the volume of genetic data processed by sequencers. In the bioinformatic scientific area, highly rated multiple sequence alignment tools, ...