Browsing Articles publicats (Informàtica i Enginyeria Industrial) by Author "Lladós Segura, Jordi"
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Accurate consistency-based MSA reducing the memory footprint
Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando; Lérida Monsó, Josep Lluís (Elsevier, 2021)Background and Objective: The emergence of Next-Generation sequencing has created a push for faster and more accurate multiple sequence alignment tools. The growing number of sequences and their longer sizes, which require ... -
High Performance computing improvements on bioinformatics consistency-based multiple sequence alignment tools
Orobitg Cortada, Miquel; Guirado Fernández, Fernando; Cores Prado, Fernando; Lladós Segura, Jordi; Notredame, Cedric (Elsevier, 2014-10-08)Multiple Sequence Alignment (MSA) is essential for a wide range of applications in Bioinformatics. Traditionally, the alignment accuracy was the main metric used to evaluate the goodness of MSA tools. However, with the ... -
Optimization of Consistency-Based Multiple Sequence Alignment using Big Data technologies
Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando (Springer, 2019)With the advent of new high-throughput next-generation sequencing technologies, the volume of genetic data processed has increased significantly. It is becoming essential for these applications to achieve large-scale alignments ... -
PPCAS: Implementation of a Probabilistic Pairwise Model for Consistency-Based Multiple Alignment in Apache Spark
Lladós Segura, Jordi; Guirado Fernández, Fernando; Cores Prado, Fernando (Springer, 2017)Large-scale data processing techniques, currently known as Big-Data, are used to manage the huge amount of data that are generated by sequencers. Although these techniques have significant advantages, few biological ... -
Recovering accuracy methods for scalable consistency library
Lladós Segura, Jordi; Guirado Fernández, Fernando; Cores Prado, Fernando; Lérida Monsó, Josep Lluís; Notredame, Cedric (Springer Verlag, 2015-05-01)Multiple sequence alignment (MSA) is crucial for high-throughput next generation sequencing applications. Large-scale alignments with thousands of sequences are necessary for these applications. However, the quality of the ... -
Scalable Consistency in T-Coffee Through Apache Spark and Cassandra Database
Lladós Segura, Jordi; Cores Prado, Fernando; Guirado Fernández, Fernando (Mary Ann Liebert, 2018)Next-generation sequencing, also known as high-throughput sequencing, has increased the volume of genetic data processed by sequencers. In the bioinformatic scientific area, highly rated multiple sequence alignment tools, ...