Now showing items 1-4 of 4

    • Exceptional human longevity is associated with a specific plasma phenotype of ether lipids 

      Pradas Barriga, Irene; Jové Font, Mariona; Huynh, Karina; Puig Farré, Josep; Inglés, Marta; Borràs, Consuelo; Viña Ribes, José; Meikle, Peter J.; Pamplona Gras, Reinald (Elsevier, 2019)
      A lipid profile resistant to oxidative damage is an inherent trait associated with animal lifespan. However, there is a lack of lipidomic studies on human longevity. Here we use mass spectrometry based technologies to ...
    • Lifelong soya consumption in males does not increase lifespan but increases health span under a metabolic stress such as type 2 diabetes mellitus 

      Borràs, Consuelo; Abdelaziz, Kheira M.; Díaz, Ana; Gambini,Juan; Jové Font, Mariona; López-Grueso, Raul; Mas-Bargues, Cristina; Monleón, Daniel; Pamplona Gras, Reinald; Viña Ribes, José (Elsevier, 2021-12-01)
      Soya consumption can decrease oxidative stress in animal models. Moreover, phytoestrogens such as genistein, present in soya, can mimic some of the beneficial effects of estrogens and are devoid of significant side effects, ...
    • Long-lived Humans Have a Unique Plasma Sphingolipidome 

      Pradas Barriga, Irene; Jové Font, Mariona; Huynh, Kevin; Inglés, Marta; Borràs, Consuelo; Mota Martorell, Natàlia; Galo-Licona, José Daniel; Puig, Josep; Viña Ribes, José; Meikle, Peter J.; Pamplona Gras, Reinald (Oxford University Press, 2022)
      A species-specific lipidome profile is an inherent feature linked to longevity in the animal kingdom. However, there is a lack of lipidomic studies on human longevity. Here, we use mass spectrometry-based lipidomics to ...
    • Redox lipidomics to better understand brain aging and function 

      Pamplona Gras, Reinald; Borràs, Consuelo; Jové Font, Mariona; Pradas Barriga, Irene; Ferrer, Isidre; Viña Ribes, José (Elsevier, 2019)
      Human prefrontal cortex (PFC) is a recently evolutionary emerged brain region involved in cognitive functions. Human cognitive abilities decline during aging. Yet the molecular mechanisms that sustain the preservation or ...