Now showing items 1-4 of 4

    • B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes 

      Egia-Mendikute, Leire; Arpa i Puigdemont, Berta; Rosell Mases, Estela; Corral-Pujol, Marta; Carrascal, Jorge; Carrillo, Jorge; Mora Giral, Concepció; Chapman, Harold; Panosa, Anaïs; Vives Pi, Marta; Stratmann, Thomas; Serreze, David; Verdaguer Autonell, Joan (Frontiers Media, 2019)
      Previous studies indicate that B-lymphocytes play a key role activating diabetogenic T-lymphocytes during the development of autoimmune diabetes. Recently, two transgenic NOD mouse models were generated: the NOD-PerIg and ...
    • In vitro cell migration, invasion, and adhesion assays: from cell imaging to data analysis 

      Pijuan, Jordi; Barceló Gómez, Carla; Moreno, David F.; Maiques Carlos, Oscar; Sisó, Pol; Marti, Rosa M.; Macià Armengol, Anna; Panosa, Anaïs (Frontiers Media, 2019-06)
      Cell migration is a key procedure involved in many biological processes includingembryological development, tissue formation, immune defense or inflammation, andcancer progression. How physical, chemical, and molecularaspects ...
    • In vivo diabetogenic action of CD41+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18 

      Wen, Li; Green, E. Allison; Stratmann, Thomas; Panosa, Anaïs; Gomis, Ramon; Eynon, Elizabeth E.; Flavell, Richard A.; Mezquita, Jovita A.; Mora Giral, Concepció (Wiley, 2011)
      CD4+ T lymphocytes are required to induce spontaneous autoimmune diabetes in the NOD (Non Obese Diabetic) mouse. Since pancreatic β cells upregulate Fas expression upon exposure to proinflammatory cytokines, we studied ...
    • T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1 

      Maiques Carlos, Oscar; Barceló Gómez, Carla; Panosa, Anaïs; Pijuan Marquilles, Jordi; Orgaz, Jose L.; Rodríguez Hernández, Irene; Matas Nadal, Clara; Tell, Gemma; Vilella, Ramón; Fabra, Angels; Puig, Susana; Sanz Moreno, Victoria; Matias-Guiu, Xavier; Cantí Nicolás, Carles; Herreros Danés, Judit; Martí Laborda, Rosa Ma.; Macià Armengol, Anna (Wiley, 2018)
      Melanoma is a malignant tumor derived from melanocytes. Once disseminated, it is usually highly resistant to chemotherapy and is associated with poor prognosis. We have recently reported that T-type calcium channels (TTCCs) ...