Browsing Medicina Experimental by Author "van den Akker, Willem M.R."

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Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution

van den Akker, Willem M.R.; Brox, Aurora; Puelles, Luis; Durston, Antony J.; Medina Hernández, Loreta Mª (Wiley, 2008)

Knockout of the Nkx2.1 (Titf-1) homeobox gene in the mouse leads to severe malformation and size reduction of the basal telencephalon/preoptic area and basal hypothalamus, indicating an important role of this gene in ...