Now showing items 1-3 of 3

    • Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age 

      Jové Font, Mariona; Cabré, Rosanna; Mota Martorell, Natàlia; Martin Garí, Meritxell; Obis, Èlia; Ramos, Paula; Canales , Iván; Galo-Licona, José Daniel; Sol, Joaquim; Nogueras Penabad, Lara; Torres Cabestany, Pascual; Portero Otín, Manuel; Ayala Jové, Ma. Victoria (Maria Victoria); Ferrer, Isidre; Pamplona Gras, Reinald (MDPI, 2021-11-20)
      Lipids are closely associated with brain structure and function. However, the potential changes in the lipidome induced by aging remain to be elucidated. In this study, we used chromatographic techniques and a mass ...
    • Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients 

      Gonzalo Benito, Hugo; Nogueras Penabad, Lara; Gil-Sánchez, Anna; Vicente Hervás, José; Valcheva, Petya; González Mingot, Cristina; Martin-Gari, Meritxell; Canudes, Marc; Peralta Moncusí, Silvia; Solana Moga, M. José; Pamplona Gras, Reinald; Portero Otín, Manuel; Boada Pallàs, Jordi; Serrano Casasola, José Carlos Enrique; Brieva Ruiz, Luis (Frontiers Media, 2019)
      Literature suggests that oxidative stress (OS) may be involved in the pathogenesis of multiple sclerosis (MS), in which the immune system is known to play a key role. However, to date, the OS in peripheral lymphocytes and ...
    • Lipid profile of cerebrospinal fluid in multiple sclerosis patients: a potential tool for diagnosis 

      Nogueras Penabad, Lara; Gonzalo Benito, Hugo; Jové Font, Mariona; Sol, Joaquim; Gil-Sánchez, Anna; Hervás, J.V.; Valcheva, Petya; González Mingot, Cristina; Solana Moga, M. José; Peralta Moncusí, Silvia; Pamplona Gras, Reinald; Brieva Ruiz, Luis (Nature Publishing Group, 2019-08-05)
      Multiple sclerosis (MS) is a complex multifactorial neuropathology. Although its etiology remains unclear, it has been demonstrated that the immune system attacks myelin, leading to demyelination and axonal damage. The ...