Now showing items 1-2 of 2

    • Mitochondria and ageing 

      Leeuwenburgh, Christiaan; Pamplona Gras, Reinald; Sanz, Alberto (Hindawi Publishing Corporation, 2011)
    • Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice 

      Hiona, Asimina; Sanz, Alberto; Kujoth, Gregory C.; Pamplona Gras, Reinald; Seo, Arnold Y.; Hofer, Tim; Someya, Shinichi; Miyakawa, Takuya; Nakayama, Chie; Samhan-Arias, Alejandro K.; Servais, Stephane; Barger, Jamie L.; Portero Otín, Manuel; Tanokura, Masaru; Prolla, Tomas A.; Leeuwenburgh, Christiaan (Public Library of Science (PLoS), 2010)
      Background: Aging results in a progressive loss of skeletal muscle, a condition known as sarcopenia. Mitochondrial DNA (mtDNA) mutations accumulate with aging in skeletal muscle and correlate with muscle loss, although no ...