Browsing Medicina Experimental by Title
Now showing items 112-131 of 325
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Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex
(Wiley, 2005)We analyzed the development of immunoreactive expression patterns for the neurotransmitter -aminobutyric acid (GABA) and the calcium-binding proteins calbindin, calretinin, and parvalbumin in the embryonic and postnatal ... -
Embryonic origin of the Islet1 and Pax6 neurons of the chicken central extended amygdala using cell migration assays and relation to different neuropeptide-containing cells
(Karger, 2015)In a recent study, we tentatively identified different subdivisions of the central extended amygdala (EAce) in chicken based on the expression of region-specific transcription factors (including Pax6 and Islet1) and several ... -
Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation
(MDPI, 2021-10-05)TGF-β has a dichotomous function, acting as tumor suppressor in premalignant cells but as a tumor promoter for cancerous cells. These contradictory functions of TGF-β are caused by different cellular contexts, including ... -
Epicatechin induces NF-kB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
(Cambridge University Press, 2010)The dietary flavonoid epicatechin has been reported to exhibit a wide range of biological activities. The objective of the present study was to investigate the time-dependent regulation by epicatechin on the activity of ... -
Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster
(Gerontological Society of AmericaOxford University Press, 2019)Aging is a multifactorial process which affects all animals. Aging as a result of damage accumulation is the most accepted explanation but the proximal causes remain to be elucidated. There is also evidence indicating that ... -
Estudio de intervención aleatorizado para evaluar la prevalencia de enfermedad ateromatosa y renal ocultas y su impacto en la morbimortalidad: Proyecto ILERVA
(Sociedad Española de Nefrología, 2016)Antecedentes y objetivos: La enfermedad renal crónica (ERC) y la ateromatosis son 2 enfermedades interrelacionadas que aumentan el riesgo de morbimortalidad cardiovascular. Los objetivos del proyecto ILERVAS son: 1) conocer ... -
Evolution of Pallial Areas and Networks Involved in Sociality: Comparison Between Mammals and Sauropsids
(Frontiers Media, 2019)Birds are extremely interesting animals for studying the neurobiological basis of cognition and its evolution. They include species that are highly social and show high cognitive capabilities. Moreover, birds rely more on ... -
Evolutionary and developmental contributions for understanding the organization of the basal ganglia
(Karger, 2014-04-24)Herein we take advantage of the evolutionary developmental biology approach in order to improve our understanding of both the functional organization and the evolution of the basal ganglia, with a particular focus on the ... -
Exceptional human longevity is associated with a specific plasma phenotype of ether lipids
(Elsevier, 2019)A lipid profile resistant to oxidative damage is an inherent trait associated with animal lifespan. However, there is a lack of lipidomic studies on human longevity. Here we use mass spectrometry based technologies to ... -
Exposure to minimally processed pear and melon during shelf life could modify the pathogenic potential of Listeria monocytogenes
(Elsevier, 2017)Survival and virulence of foodborne pathogens can be influenced by environmental factors such as the intrinsic properties of food as well as the extrinsic properties that contribute to food shelf life (e.g., temperature ... -
Expression of cLhx6 and cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis
(Elsevier, 2008)We investigated the origin of the avian bed nucleus of the stria terminalis (BST) and other parts of the avian subpallial amygdala, by studying the expression of the LIM-homeobox chick genes Lhx6 (cLhx6) and Lhx7/8 (cLhx7/8) ... -
Expression of regulatory genes in the embryonic brain of a lizard and implications for understanding pallial organization and evolution
(Wiley, 2017)The comparison of gene expression patterns in the embryonic brain of mouse and chicken is being essential for understanding pallial organization. However, the scarcity of gene expression data in reptiles, crucial for ... -
Expression patterns of developmental regulatory genes show comparable divisions in the telencephalon of Xenopus and mouse: insights into the evolution of the forebrain
(Elsevier, 2005)In this study, we review data on the existence of comparable divisions and subdivisions in the telencephalon of different groups of tetrapods based on expression of some developmental regulatory genes, having a particular ... -
Faecal bacterial and short-chain fatty acids signature in hypercholesterolemia
(Nature Research, 2019)Gut microbiota has been suggested to affect lipid metabolism. The objective of this study was to characterize the faecal microbiota signature and both short chain fatty acids (SCFAs) and bile acids (BA) profile of ... -
FAK inhibition induces glioblastoma cell senescence-like state through p62 and p27
(MDPI, 2020-04-27)Focal adhesion kinase (FAK) is a central component of focal adhesions that regulate cancer cell proliferation and migration. Here, we studied the effects of FAK inhibition in glioblastoma (GBM), a fast growing brain tumor ... -
La farmacologia de la coagulació plasmàtica per via oral al segle XXI
(Col·legi Oficial de Metges de Lleida, 2012) -
Fatty acids in the placenta of appropiate- versus small-for-gestational-age infants at term birth
(Elsevier, 2021)Introduction: Fatty acids are essential nutrients for the fetus and are supplied by the mother through the placenta. Desaturase and elongase enzymes play an important role in modulating the fatty acid composition of body ... -
Formation of S-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction
(Springer Verlag, 2013)Maillard reaction contributes to the chemical modification and cross-linking of proteins. This process plays a significant role in the aging process and determination of animal longevity. Oxidative conditions promote the ... -
Functional analysis of the cysteine residues and the repetitive sequence of Saccharomyces cerevisiae Pir4/Cis3: the repetitive sequence is needed for binding to the cell wall beta-1,3-glucan.
(Wiley InterScience, 2003-08)Identification of PIR/CIS3 gene was carried out by amino-terminal sequencing of a protein band released by β-mercaptoethanol (β-ME) from S. cerevisiae mnn9 cell walls. The protein was released also by digestion with ... -
Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity
(Springer, 2020-08-01)Maximum longevity (ML) varies significantly across animal species, but the underlying molecular mechanisms remain poorly understood. Recent studies and omics approaches suggest that phenotypic traits of ML could to converge ...