Now showing items 339-351 of 351

    • Up-Regulation of Specific Bioactive Lipids in Celiac Disease 

      Martín Masot, Rafael; Galo-Licona, José Daniel; Mota Martorell, Natàlia; Sol, Joaquim; Jové Font, Mariona; Maldonado, José; Pamplona Gras, Reinald; Nestares, Teresa (MDPI, 2021)
      Celiac disease (CD) is an autoimmune enteropathy linked to alterations of metabolism. Currently, limited untargeted metabolomic studies evaluating differences in the plasma metabolome of CD subjects have been documented. ...
    • Use of Autoantigen-Loaded Phosphatidylserine-Liposomes to Arrest Autoimmunity in Type 1 Diabetes 

      Pujol Autonell, Irma; Serracant Prat, Arnau; Cano Sarabia, Antonia María; Ampudia, Rosa Maria; Rodríguez Fernández, Silvia; Sánchez (Sànchez Pla), Álex; Izquierdo, Cristina; Stratmann, Thomas; Puig-Domingo, Manuel; Maspoch, Daniel; Verdaguer Autonell, Joan; Vives Pi, Marta (Public Library Science, 2015-06-03)
    • Usefulness of imaging techniques and novel biomarkers in the prediction of cardiovascular risk in patients with chronic kidney disease in Spain: The NEFRONA project 

      Junyent, Mireia; Martínez Alonso, Montserrat; Borràs, Mercè; Betriu i Bars, M. Àngels; Coll, Blai; Craver Hospital, Lourdes; Marco Mayayo, M. Paz; Sarró, Felipe; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (Sociedad Española de Nefrologia, 2010)
      Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). Cardiovascular risk assessment in this population is hampered by the failure of ...
    • Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy 

      Fourcade, Stéphane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudí i Farré, Alba; Portero Otín, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona Gras, Reinald; Aubourg, Patrick; Pujol, Aurora (Oxford University Press, 2010)
      X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurometabolic disease. It results from the functional loss of a member of the peroxisomal ATP-binding cassette transporter subfamily D (ABCD1), ...
    • Vascular calcification induced by chronic kidney disease is mediated by an increase of 1α-hydroxylase expression in vascular smooth muscle cells 

      Torremadé Pascual, Noèlia; Bozić Stanojević, Milica; Panizo García, Sara; Barrio Vazquez, Sara; Fernandez Martín, José L.; Encinas Martín, Mario; Goltzman, David; Arcidiacono, Maria V.; Fernández i Giráldez, Elvira; Valdivielso Revilla, José Manuel (Wiley, 2016-04-01)
      Vascular calcification (VC) is a complication of chronic kidney disease that predicts morbidity and mortality. Uremic serum promotes VC, but the mechanism involved is unknown. A role for 1,25(OH)2 D3 in VC has been proposed, ...
    • Vector description of electric and hydrophobic interactions in protein homodimers 

      Mozo Villarías, Angel; Cedano, Juan; Querol, Enrique (Springer, 2016)
      This article describes the formation of homodimers from their constituting monomers, based on the rules set by a simple model of electric and hydrophobic interactions. These interactions are described in terms of the ...
    • Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile 

      Serrano Casasola, José Carlos Enrique; de Lorenzo, David; Cassanyé, Anna; Martín Garí, Meritxell; Espinel, Alberto; Delgado, Marco Antonio; Pamplona Gras, Reinald; Portero Otín, Manuel (Springer Verlag, 2013)
      Vitamin D receptor polymorphisms may predispose that not all individuals could have benefits from the nutritional supplementation of 25-hydroxyvitamin D. Furthermore, vitamin D-related cardiovascular effects may also ...
    • Voltage-gated calcium channel blockers deregulate macroautophagy in cardiomyocytes 

      Pushparaj, Charumathi; Das, Arindam; Purroy, Rosa; Nàger Grifo, Mireia; Herreros Danés, Judit; Pamplona Gras, Reinald; Cantí Nicolás, Carles (Elsevier, 2015)
      Voltage-gated calcium channel blockers are widely used for the management of cardiovascular diseases, however little is known about their effects on cardiac cells in vitro. We challenged neonatal ventricular cardiomyocytes ...
    • Weak Association between Skin Autofluorescence Levels and Prediabetes with an ILERVAS Cross-Sectional Study 

      Sánchez Peña, Enric; Kerkeni, M.; Hernández García, Marta; Gavaldá, Ricard; Rius, Ferran; Sauret, Ariadna; Torres, Gerard; Bermúdez López, Marcelino; Fernández i Giráldez, Elvira; Castro-Boqué, Eva; Purroy Garcia, Francisco; Mauricio Puente, Dídac; Farràs-Sallés, Cristina; Buti, Miquel; Godoy i García, Pere; Pamplona Gras, Reinald; Lecube Torelló, Albert (MDPI, 2022)
      A large body of evidence demonstrates a relationship between hyperglycemia and increased concentrations of advanced glycation end-products (AGEs). However, there is little information about subcutaneous AGE accumulation ...
    • When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts 

      Jové Font, Mariona; Serrano Casasola, José Carlos Enrique; Bellmunt i Curcó, Josepa; Cassanyé, Anna; Anglès, Neus; Reguant, Jordi; Morelló, José R.; Pamplona Gras, Reinald; Portero Otín, Manuel (BioMed Central, 2010)
      Background: Experimental evidences demonstrate that vegetable derived extracts inhibit cholesterol absorption in the gastrointestinal tract. To further explore the mechanisms behind, we modeled duodenal contents with several ...
    • Whole-brain dynamics in aging: disruptions in functional connectivity and the role of the rich club 

      Escrichs, Anira; Biarnés, Carles; Garre Olmo, Josep; Fernández Real, Xavier; Ramos, Rafel; Pamplona Gras, Reinald; Brugada, Ramon; Serena, Joaquín; Ramió Torrentà, Lluís; Coll-De-Tuero, Gabriel; Gallart, Luís; Barretina Ginesta, Jordi; Vilanova, Joan Carles; Mayneris Perxachs, Jordi; Essig, Marco; Figley, Chase R.; Pedraza, Salvador; Puig, Josep; Deco, Gustavo (Oxford University Press, 2021)
      Normal aging causes disruptions in the brain that can lead to cognitive decline. Resting-state functional magnetic resonance imaging studies have found significant age-related alterations in functional connectivity across ...
    • Wnt-3a and Wnt-3 differently stimulate proliferation and neurogenesis of spinal neural precursors and promote neurite outgrowth by canonical signaling 

      David, Mónica Delia; Cantí Nicolás, Carles; Herreros Danés, Judit (Wiley, 2010)
      Wnt factors regulate neural stem cell development and neuronal connectivity. Here we investigated whether Wnt-3a and Wnt-3, expressed in the developing spinal cord, regulate proliferation and the neuronal differentiation ...
    • β-catenin signalling in Glioblastoma multiforme and Glioma-initiating cells 

      Nàger Grifo, Mireia; Bhardwaj, Deepshikha; Cantí Nicolás, Carles; Medina Hernández, Loreta Mª; Nogués Bara, Pere; Herreros Danés, Judit (Hindawi Publishing Corporation, 2012)
      Glioblastoma multiforme (GBM) is a commonly occurring brain tumor with a poor prognosis. GBM can develop both “de novo” or evolve from a previous astrocytoma and is characterized by high proliferation and infiltration into ...