Browsing Medicina Experimental by Title
Now showing items 96-115 of 300
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Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS
(BioMed Central, 2016)Introduction: Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with a gender bias towards major prevalence in male individuals. Several data suggest the involvement of oxidative stress and mitochondrial dysfunction ... -
Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver
(Springer Verlag, 2007)Previous studies have consistently shown that 40% caloric restriction (CR) decreases the rate of mitochondrial ROS production and steady-state levels of markers of oxidative damage to macromolecules including mitochondrial ... -
Effect of dietary bioactive compounds on mitochondrial and metabolic flexibility
(MDPI, 2016-03)Metabolic flexibility is the capacity of an organism to adequately respond to changes in the environment, such as nutritional input, energetic demand, etc. An important player in the capacity of adaptation through different ... -
Effect of Pseudomonas graminis strain CPA-7 on the ability of Listeria monocytogenes and Salmonella enterica subsp. enterica to colonize Caco-2 cells after pre-incubation on fresh-cut pear
(Elsevier, 2017)To further gain insight into the mechanism by which the biopreservative bacterium Pseudomonas graminis CPA-7 develops its antimicrobial activity, we have examined the effect that the prior interaction stablished by this ... -
Effects of aging and methionine restriction on rat kidney metabolome
(MDPI, 2019-11-14)Methionine restriction (MetR) in animal models extends maximum longevity and seems to promote renoprotection by attenuating kidney injury. MetR has also been proven to affect several metabolic pathways including lipid ... -
Effects of Mediterranean Diet and Physical Activity on Pulmonary Function: A Cross-Sectional Analysis in the ILERVAS Project
(MDPI, 2019)A few studies showed that both adherence to Mediterranean diet (MedDiet) and physical activity practice have a positive impact on pulmonary function in subjects with lung disease. These associations are not well studied ... -
Efferocytosis promotes suppressive effects on dendritic cells through prostaglandin E2 production in the context of autoimmunity
(Public Library of Science, 2013)Introduction: Efferocytosis is a crucial process by which apoptotic cells are cleared by phagocytes, maintaining immune tolerance to self in the absence of inflammation. Peripheral tolerance, lost in autoimmune processes, ... -
Efficacy and tolerance of the topical application of potassium hydroxide (10% and 15%) in the treatment of molluscum contagiosum: Randomized clinical trial: Research protocol
(BioMed Central, 2011)Background: Molluscum contagiosum is a non-severe pediatric viral infection. Because it is highly contagious and current treatments have negative aesthetic and psychological effects, we want to test an alternative treatment ... -
Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex
(Wiley, 2005)We analyzed the development of immunoreactive expression patterns for the neurotransmitter -aminobutyric acid (GABA) and the calcium-binding proteins calbindin, calretinin, and parvalbumin in the embryonic and postnatal ... -
Embryonic origin of the Islet1 and Pax6 neurons of the chicken central extended amygdala using cell migration assays and relation to different neuropeptide-containing cells
(Karger, 2015)In a recent study, we tentatively identified different subdivisions of the central extended amygdala (EAce) in chicken based on the expression of region-specific transcription factors (including Pax6 and Islet1) and several ... -
Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation
(MDPI, 2021-10-05)TGF-β has a dichotomous function, acting as tumor suppressor in premalignant cells but as a tumor promoter for cancerous cells. These contradictory functions of TGF-β are caused by different cellular contexts, including ... -
Epicatechin induces NF-kB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells
(Cambridge University Press, 2010)The dietary flavonoid epicatechin has been reported to exhibit a wide range of biological activities. The objective of the present study was to investigate the time-dependent regulation by epicatechin on the activity of ... -
Estudio de intervención aleatorizado para evaluar la prevalencia de enfermedad ateromatosa y renal ocultas y su impacto en la morbimortalidad: Proyecto ILERVA
(Sociedad Española de Nefrología, 2016)Antecedentes y objetivos: La enfermedad renal crónica (ERC) y la ateromatosis son 2 enfermedades interrelacionadas que aumentan el riesgo de morbimortalidad cardiovascular. Los objetivos del proyecto ILERVAS son: 1) conocer ... -
Evolution of Pallial Areas and Networks Involved in Sociality: Comparison Between Mammals and Sauropsids
(Frontiers Media, 2019)Birds are extremely interesting animals for studying the neurobiological basis of cognition and its evolution. They include species that are highly social and show high cognitive capabilities. Moreover, birds rely more on ... -
Evolutionary and developmental contributions for understanding the organization of the basal ganglia
(Karger, 2014-04-24)Herein we take advantage of the evolutionary developmental biology approach in order to improve our understanding of both the functional organization and the evolution of the basal ganglia, with a particular focus on the ... -
Exceptional human longevity is associated with a specific plasma phenotype of ether lipids
(Elsevier, 2019)A lipid profile resistant to oxidative damage is an inherent trait associated with animal lifespan. However, there is a lack of lipidomic studies on human longevity. Here we use mass spectrometry based technologies to ... -
Exposure to minimally processed pear and melon during shelf life could modify the pathogenic potential of Listeria monocytogenes
(Elsevier, 2017)Survival and virulence of foodborne pathogens can be influenced by environmental factors such as the intrinsic properties of food as well as the extrinsic properties that contribute to food shelf life (e.g., temperature ... -
Expression of cLhx6 and cLhx7/8 suggests a pallido-pedunculo-preoptic origin for the lateral and medial parts of the avian bed nucleus of the stria terminalis
(Elsevier, 2008)We investigated the origin of the avian bed nucleus of the stria terminalis (BST) and other parts of the avian subpallial amygdala, by studying the expression of the LIM-homeobox chick genes Lhx6 (cLhx6) and Lhx7/8 (cLhx7/8) ... -
Expression of regulatory genes in the embryonic brain of a lizard and implications for understanding pallial organization and evolution
(Wiley, 2017)The comparison of gene expression patterns in the embryonic brain of mouse and chicken is being essential for understanding pallial organization. However, the scarcity of gene expression data in reptiles, crucial for ... -
Expression patterns of developmental regulatory genes show comparable divisions in the telencephalon of Xenopus and mouse: insights into the evolution of the forebrain
(Elsevier, 2005)In this study, we review data on the existence of comparable divisions and subdivisions in the telencephalon of different groups of tetrapods based on expression of some developmental regulatory genes, having a particular ...