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  • Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation. 

    Eritja Sánchez, Núria; Navaridas Fernández de Bobadilla, Raúl; Ruiz Mitjana,Anna; Vidal Sabanés, Maria; Egea Navarro, Joaquim; Encinas Martín, Mario; Matias-Guiu, Xavier; Dolcet Roca, Xavier (MDPI, 2021-10-05)
    TGF-β has a dichotomous function, acting as tumor suppressor in premalignant cells but as a tumor promoter for cancerous cells. These contradictory functions of TGF-β are caused by different cellular contexts, including ...
  • Sex-Related Differences in Clinical Features, Neuroimaging, and Long-Term Prognosis After Transient Ischemic Attack 

    Purroy Garcia, Francisco; Vicente-Pascual, Mikel; Arque, Gloria; Baraldes-Rovira, Mariona; Begué Gómez, Robert; Gallego, Yhovany; Gil, M. Isabel; Gil-Villar, María Pilar; Mauri, Gerard; Quilez Martínez, Alejandro; Sanahuja Montesinos, Jordi; Vazquez-Justes, Daniel (American Heart Association, 2021)
    Differences in sex in the incidence, presentation, and outcome of events after ischemic stroke have been studied in depth. In contrast, only limited data are available after transient ischemic attack (TIA). We aim to assess ...
  • Circadian Patterns of Patients with Type 2 Diabetes and Obstructive Sleep Apnea 

    Cambras, Trinitat; Romero, Odile; Díez Noguera, Antoni; Lecube Torelló, Albert; Sampol, Gabriel (MDPI, 2021)
    Sleep apnea, a condition that modifies sleep and circadian rhythms, is highly prevalent in patients with diabetes. However, it is not known if there is an association between sleep apnea, circadian alterations and glycemic ...
  • Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges 

    Vilarrasa, Núria; San Jose, Patricia; Rubio, Miguel Ángel; Lecube Torelló, Albert (Dove Medical Press, 2021)
    Obesity affects large numbers of patients with type 1 diabetes (T1D) across their lifetime, with rates ranging between 2.8% and 37.1%. Patients with T1D and obesity are characterized by the presence of insulin resistance, ...
  • Eutanasia: ¿es esta la ley que necesitamos? 

    Altisent, Rogelio; Nabal Vicuña, Maria; Muñoz, Pablo; Ferrer, Sandra; Delgado-Marroquín, María Teresa; Alonso, Alberto (Elsevier, 2021)
    La Ley de Eutanasia española introduce un nuevo derecho que se incorpora a la cartera de servicios del sistema sanitario, como una prestación cuya aplicación se garantiza en el plazo de 40 días. Desde la experiencia clínica ...
  • Prevalence, clinical characteristics, and outcome of pleural effusions in ovarian cancer 

    Porcel Pérez, José Manuel; Murata, Paola; Porcel, Laura; Bielsa Martín, Silvia; Pardina, Marina; Salud Salvia, Maria Antonieta (De Gruyter, 2021)
    Objectives: The prevalence, clinical characteristics and prognosis of pleural effusions (PEs) associated with ovarian cancer (OC) have seldom been addressed systematically, as in the current investigation. Methods: All ...
  • Non‑linear association of anthropometric measurements and pulmonary function 

    Zhang, Rui‑Heng; Zhou, Jian‑Bo; Cai, Yao‑Hua; Shu, Lin‑Ping; Yang, Jinkui; Wei, Wenbin; Lecube Torelló, Albert (Nature Research, 2021)
    This study examined the association of anthropometric measurements [body mass index (BMI), waist circumference (WC), percentage body fat (PBF), body roundness index (BRI) and A Body Shape Index (ABSI)] with pulmonary ...
  • Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma 

    Sanegre, Sabina; Eritja Sánchez, Núria; De Andrea, Carlos; Diaz-Martin, Juan; Diaz-Lagares, Ángel; Jácome, María Amalia; Salguero-Aranda, Carmen; García Ros, David; Davidson, Ben; Lopez, Rafel; Melero, Ignacio; Navarro, Samuel; Ramon y Cajal, Santiago; Alava, Enrique de; Matias-Guiu, Xavier; Noguera, Rosa (Frontiers Media, 2021)
    The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular ...
  • Identifying thoracic malignancies through pleural fluid biomarkers: a predictive multivariate model 

    Porcel Pérez, José Manuel; Esquerda, Aureli; Martínez Alonso, Montserrat; Bielsa Martín, Silvia; Salud Salvia, Maria Antonieta (Wolters Kluwer Health, 2016-03-01)
    The diagnosis of malignant pleural effusions may be challenging when cytological examination of aspirated pleural fluid is equivocal or noncontributory. The purpose of this study was to identify protein candidate biomarkers ...
  • Ganancia de peso durante el confinamiento por la COVID-19; encuesta de la Sociedad Española de Obesidad 

    López de la Torre, Martín; Bellido, Diego; Monereo, Susana; Lecube Torelló, Albert; Sánchez Peña, Enric; Tinahones, Francisco José (Sociedad Española de Cirugía de Obesidad y Metabólica y Sociedad Española para el Estudio de la Obesidad, 2020-11-01)
    La obesidad, después de la edad, es el principal factor de mal pronóstico durante la infección por la COVID-19. El confinamiento al que la población española ha sido expuesta durante varias semanas puede ser una causa de ...
  • Revisión sistemática del síndrome de Münchhausen por poderes o trastorno facticio impuesto a otro: psicobiografía de la perpertradora, el proceso de peregrinación hospitalaria y signos de alarma en la víctima 

    Baena Marí, I.; Beltrán Mallén, D.; Pifarré Paredero, Josep (Sociedad Española de Medicina Psicosomática, 2020-10)
    INTRODUCCIÓN: En 1977, Roy Medow acuña y describe el síndrome de Münchhausen por poderes como una enfermedad mental en la que una cuidadora miente al doctor sobre la salud de su hijo mediante la fabricación de signos ...
  • Effect of CPAP Therapy on 24-Hour Intraocular Pressure-Related Pattern From Contact Lens Sensors in Obstructive Sleep Apnea Syndrome 

    Muniesa Royo, Ma. Jesús; Benítez, Iván; Ezpeleta, Juan Antonio; Sánchez de la Torre, Manuel; Pazos, Marta; Millà, Elena; Barbé Illa, Ferran (Association for Research in Vision and Ophthalmology, 2021-04-01)
    Purpose: To evaluate the effect of continuous positive airway pressure (CPAP) therapy on 24-hour intraocular pressure (IOP)-related pattern from contact lens sensors (CLS) in obstructive sleep apnea syndrome (OSAS). Methods: ...
  • Influence of thromboembolic events in the prognosis of COVID-19 hospitalized patients. Results from a cross sectional study 

    Purroy Garcia, Francisco; Arqué, G. (Public Library of Science, 2021)
    Background COVID-19 may predispose to both venous and arterial thromboembolism event (TEE). Reports on the prevalence and prognosis of thrombotic complications are still emerging. Objective To describe the rate of TEE ...
  • Clinical Usefulness of Anthropometric Indices to Predict the Presence of Prediabetes. Data from the ILERVAS Cohort 

    Sánchez, Marta; Sánchez Peña, Enric; Bermúdez López, Marcelino; Torres, Gerard; Farràs-Sallés, Cristina; Pamplona Gras, Reinald; Castro-Boqué, Eva; Valdivielso Revilla, José Manuel; Purroy Garcia, Francisco; Martínez Alonso, Montserrat; Godoy i García, Pere; Mauricio Puente, Dídac; Fernández i Giráldez, Elvira; Hernández García, Marta; Rius, Ferran; Lecube Torelló, Albert (MDPI, 2021-03-23)
    Prediabetes is closely related to excess body weight and adipose distribution. For this reason, we aimed to assess and compare the diagnostic usefulness of ten anthropometric adiposity indices to predict prediabetes. ...
  • Prognostic value of symptoms at lung cancer diagnosis: a three-year observational study 

    Polanco, Dinora; Pinilla, Lucía; Gracia-Lavedan, Esther; Mas, Anna; Bertran, Sandra; Fierro, Gemma; Seminario, Asunción; Gómez Falguera, Silvia; Barbé Illa, Ferran (AME Publishing, 2021-03)
    Background: Lung cancer is mainly diagnosed at advanced or locally advanced stages, usually when symptoms become evident. However, sometimes it may be diagnosed incidentally during routine care, while patients are still ...
  • Implementing Mobile Health–Enabled Integrated Care for Complex Chronic Patients: Intervention Effectiveness and Cost-Effectiveness Study 

    Batlle Garcia, Jordi de; Massip, Mireia; Vargiu, Eloisa; Nadal Braque, Núria; Fuentes Botargues, Araceli; Ortega Bravo, Marta; Miralles, Felip; Barbé Illa, Ferran; Torres, Gerard (JMIR Publications, 2021)
    Background: Integrated care can generate health and social care efficiencies through the defragmentation of care and adoption of patient-centered preventive models. eHealth can be a key enabling technology for integrated ...
  • Dermatological Manifestations in the Intensive Care Unit: A Practical Approach 

    Badia Castello, Mariona; Casanova i Seuma, Josep M. (Josep Manel); Servià Goixart, Lluís; Montserrat, Neus; Codina, Jordi; Trujillano Cabello, Javier (Hindawi, 2020-09-26)
    Dermatological problems are not usually related to intensive medicine because they are considered to have a low impact on the evolution of critical patients. Despite this, dermatological manifestations (DMs) are relatively ...
  • Molecular Classification of Grade 3 Endometrioid Endometrial Cancers Identifies Distinct Prognostic Subgroups 

    Bosse, Tjalling; Nout, Remi; McAlpine, Jessica N.; McConechy, Melissa; Britton, Heidi; Hussein, Yaser; Gonzalez, Carlene; Ganesan, Raji; Steele, Jane C.; Harrison, Beth T.; Oliva, Esther; Vidal, August; Matias-Guiu, Xavier; Abu-Rustum, Nadeem R.; Levine, Douglas A.; Gilks, C. Blake; Soslow, Robert A. (Wolters Kluwer Health, 2018)
    Our aim was to investigate whether molecular classification can be used to refine prognosis in grade 3 endometrial endometrioid carcinomas (EECs). Grade 3 EECs were classified into 4 subgroups: p53 abnormal, based on ...
  • Redefining Stage I Endometrial Cancer: Incorporating Histology, a Binary Grading System, Myometrial Invasion, and Lymph Node Assessment 

    Barlin, Joyce N.; Soslow, Robert A.; Lutz, Megan; Zhou, Qin C.; St Clair, Caryn M.; Leitao, Mario M.; Iasonos, Alexia; Hensley, Martee L.; Barakat, Richard R.; Matias-Guiu, Xavier; Abu-Rustum, Nadeem R. (BMJ Publishing Group, 2013)
    Objective: We propose a new staging system for stage I endometrial cancer and compare its performance to the 1988 and 2009 International Federation of Gynecology and Obstetrics (FIGO) systems. Methods: We analyzed patients ...
  • Lipid management in patients with chronic kidney disease 

    Ferro, Charles J.; Mark, Patrick B.; Kanbay, Mehmet; Sarafidis, Pantelis; Heine, Gunnar H.; Rossignol, Patrick; Massy, Ziad A.; Mallamaci, Francesca; Valdivielso Revilla, José Manuel; Malyszko, Jolanta; Verhaar, Marianne C.; Ekart, Robert; Vanholder, Raymond; London, Gerard; Ortiz, Alberto; Zoccali, Carmine (Nature Research, 2018)
    An increased risk of cardiovascular disease, independent of conventional risk factors, is present even at minor levels of renal impairment and is highest in patients with end-stage renal disease (ESRD) requiring dialysis. ...

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