Now showing items 1-2 of 2

    • Neuronal damage induced by perinatal asphyxia is attenuated by postinjury glutaredoxin-2 administration 

      Romero, Juan Ignacio; Holubiec, Mariana Inés; Logica, Tamara; Rivière, Stéphanie; Hanschmann, Eva Maria; Kölliker Frers, Rodolfo; Tau, Julia; Blanco Calvo, Eduardo; Galeano, Pablo; Rodríguez de Fonseca, Fernando; Horst Lillig, Christopher; Capani, Francisco (Hindawi Publishing Corporation, 2017)
      The general disruption of redox signaling following an ischemia-reperfusion episode has been proposed as a crucial component in neuronal death and consequently brain damage. Thioredoxin (Trx) family proteins control redox ...
    • Thioredoxin 1 and glutaredoxin 2 contribute to maintain the phenotype and integrity of neurons following perinatal asphyxia 

      Romero, Juan Ignacio; Hanschmann, Eva Maria; Gellert,Manuela; Eitner,Susanne; Holubiec, Mariana Inés; Blanco Calvo, Eduardo; Lillig, Christopher Horst; Capani, Francisco (Elsevier, 2015-06-01)
      BACKGROUND: Thioredoxin (Trx) family proteins are crucial mediators of cell functions via regulation of the thiol redox state of various key proteins and the levels of the intracellular second messenger hydrogen peroxide. ...