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Now showing items 1-20 of 7982

    • 1,25-Dihydroxyvitamin D3 regulates VEGF production through a vitamin D response element in the VEGF promoter 

      Cardús i Figueras, Anna; Panizo García, Sara; Encinas Martín, Mario; Dolcet Roca, Xavier; Gallego, Carme; Aldea, Martí; Fernandez, Elvira; Valdivielso Revilla, José Manuel (Elsevier, 2009)
      In previous studies we have demonstrated that the active form of vitamin D (1,25(OH)2D3) increases vascular endothelial growth factor (VEGF) expression and release in vascular smooth muscle cells (VSMC) in vitro. However, ...

    • 100 casos de derecho de daños (2004-2009) 

      Salvador Coderch, Pablo; Ramos González, Sonia; Alascio Carrasco, Laura; Farnós Amorós, Esther; Fernández Crende, Antonio; Marín García, Ignacio; Milà Rafel, Rosa; Riera Roca, Magalí; Ruiz García, Carlos Alb. (Universitat Pompeu Fabra, 2010)
      InDret presenta, por sexto año consecutivo, una selección de veinte sentencias sobre responsabilidad civil dictadas por el Tribunal Supremo que tratan cuestiones centrales del derecho de daños. El lector también encontrará ...

    • 1001 Inventions. Discover The Muslim Heritage In Our World (Science Museum, Londres) 

      Llonch Molina, Nayra (Universitat de Lleida. Departament de Didàctiques EspecífiquesEdiciones Trea, 2010)

    • 128 x 128 CMOS Image Sensor With Analog Memory for Synchronous Image Capture 

      Chapinal, Genis; Bota, Sebastian A.; Moreno, Mauricio; Palacín Roca, Jordi; Herms, Atilà (Institute of Electrical and Electronic Engineers, 2002)
      A 128 x 128 CMOS imager that permits synchronous capture is presented. The sensor combines the best of CMOS imagers (low-power, random readout, nondestructive readout, single supply voltage…) and synchronous capture ...

    • 2-phenylethynesulfonamide (PES) uncovers a necrotic process regulated by oxidative stress and p53 

      Mattiolo, Paolo; Barbero-Farran A.; Yuste Mateos, Víctor J. (Víctor José); Boix Torras, Jacint; Ribas i Fortuny, Judit (Elsevier, 2014)
      2-Phenylethynesulfonamide (PES) or pifithrin-μ is a promising anticancer agent with preferential toxicity for cancer cells. The type of cell death and the molecular cascades activated by this compound are controversial. ...

    • 2-phenylethynesulphonamide (PFT-μ) enhances the anticancer effect of the novel hsp90 inhibitor NVP-AUY922 in melanoma, by reducing GSH levels 

      Yeramian Hakim, Andree; Veà Jódar, Àlvar; Benítez, Sandra; Ribera i Calvet, Joan; Domingo, Mónica; Santacana Espasa, Maria; Martínez Alonso, Montserrat; Maiques Carlos, Oscar; Valls Marsal, Joan; Dolcet Roca, Xavier; Vilella, Ramón; Cabiscol Català, Elisa; Matias-Guiu, Xavier; Marti, Rosa M. (Wiley online library, 2016)
      Heat shock proteins (HSPs), are molecular chaperones that assist the proper folding of nascent proteins. This study aims to evaluate the antitumour effects of the hsp90 inhibitor NVP-AUY922 in melanoma, both in vitro ...

    • 21st century climate change threatens mountain flora unequally across Europe 

      Engler, Robin; Randin, Christophe F.; Thuiller, Wilfried; Dullinger, Stefan; Zimmermann, Niklaus E.; Araújo, Miguel B.; Pearman, Peter B.; Le Lay, Gwenaëlle; Piedallu, Christian; Albert, Cécile H.; Choler, Philippe; Coldea, Gheorghe; de Lamo, Xavier; Dirnböck, Thomas; Gégout, Jean-Claude; Gómez García, Daniel; Grytnes, John Arvid; Heegaard, Einar; Hoistad, Fride; Nogués Bravo, David; Normand, Signe; Puscas, Mihai; Sebastià, Ma. T.; Stanisci, Angela; Theurillat, Jean-Paul; Trivedi, Mandar R.; Vittoz, Pascal; Guisan, Antoine (Blackwell Publishing Ltd, 2011)
      Continental-scale assessments of 21st century global impacts of climate change on biodiversity have forecasted range contractions for many species. These coarse resolution studies are, however, of limited relevance for ...

    • 40 casos de Derecho de daños (2004-2007) 

      Ramos González, Sonia; Marín García, Ignacio; Milà Rafel, Rosa; Ruiz García, Carlos Alb.; Farnós Amorós, Esther; Alascio Carrasco, Laura; Fernández Crende, Antonio (Universitat Pompeu Fabra, 2008)
      InDret presenta, por cuarto año consecutivo, una selección de diez sentencias del Tribunal Supremo sobre cuestiones centrales del derecho de daños. El lector también encontrará en este trabajo las selecciones de 2004, ...

    • 7-Bromoindirubin-3'-oxime induces caspase-independent cell death 

      Ribas i Fortuny, Judit; Bettayeb, Karima; Ferandin, Yoan; Knockaert, Marie; Garrofé Ochoa, Xènia; Totzke, Frank; Schächtele, Christoph; Mester, Jan; Polychronopoulos, Panagiotis; Magiatis, Prokopios; Skaltsounis, Alexios-Leandros; Boix Torras, Jacint; Meijer, Laurent (Nature Publishing Group, 2006)
      Indirubin, an isomer of indigo, is a reported inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3) as well as an agonist of the aryl hydrocarbon receptor (AhR). Indirubin is the active ...

    • 7-Bromoindirubin-3'-oxime uncovers a serine protease-mediated paradigm of necrotic cell death 

      Ribas i Fortuny, Judit; Yuste Mateos, Víctor J. (Víctor José); Garrofé Ochoa, Xènia; Meijer, Laurent; Esquerda Colell, Josep; Boix Torras, Jacint (Elsevier, 2008)
      The new 7-bromoindirubin-3′-oxime (7BIO) compound induces caspase-independent cell death in all cell lines tested to date. Irrespective of the cell line, a 25 μM treatment for 24 h is lethal for the entire cell population. ...

    • 7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome 

      Gou Fàbregas, Myriam; Macià Armengol, Anna; Anerillas, Carlos; Vaquero, Marta; Jové Font, Mariona; Jain, Sanjay; Ribera i Calvet, Joan; Encinas Martín, Mario (Nature Publishing Group, 2016)
      Smith-Lemli-Opitz syndrome (SLOS) is a rare disorder of cholesterol synthesis. Affected individuals exhibit growth failure, intellectual disability and a broad spectrum of developmental malformations. Among them, renal ...

    • 80 casos de Derecho de daños (2004-2008) 

      Ramos González, Sonia; Marín García, Ignacio; Milà Rafel, Rosa; Ruiz García, Carlos Alb.; Farnós Amorós, Esther; Alascio Carrasco, Laura; Fernández Crende, Antonio (Universitat Pompeu Fabra, 2009)
      InDret presenta, por quinto año consecutivo, una selección de cuarenta sentencias sobre responsabilidad civil dictadas por el Tribunal Supremo que tratan cuestiones centrales del derecho de daños. El lector también ...

    • A alteridade na Literatura Infantil contemporânea publicada no espaço ibérico: algumas vozes e configurações na construção do género 

      Fraga de Azevedo, Fernando; Balça, Àngela; Selfa Sastre, Moisés; Cruz, Judite Zamith (Universidade de Santiago de Compostela, 2015-12-15)
      Muchos textos de la literatura infantil, por su relación con los propósitos formativos, han valorizado ciertos puntos de vista compatibles con las comunidades socio-culturales y los valores ideológicos dominantes. Esto no ...

    • A Bayesian analysis of the effect of selection for growth rate on growth curves in rabbits 

      Blasco, Agustín; Piles, Miriam; Varona Aguado, Luís (BioMed Central, 2003)
      Gompertz growth curves were tted to the data of 137 rabbits from control (C) and selected (S) lines. The animals came from a synthetic rabbit line selected for an increased growth rate. The embryos from generations 3 ...

    • A bivalent dendrimeric peptide bearing a T-cell epitope from foot-and-mouth disease virus protein 3A improves humoral response against classical swine fever virus 

      Bohórquez, José Alejandro; Defaus, Sira; Muñoz González, Sara; Perez-Simó, Marta; Rosell, Rosa; Fraile Sauce, Lorenzo José; Sobrino, Francisco; Andreu, David; Ganges, Llilianne (Elsevier, 2017)
      Three dendrimeric peptides were synthesized in order to evaluate their immunogenicity and their potential protection against classical swine fever virus (CSFV) in domestic pigs. Construct 1, an optimized version of a ...

    • A blow-up method to prove formal integrability for some planar differential systems 

      Fercec, Brigita; Giné, Jaume (Shanghai Normal University & Wilmington Scientific Publisher, 2018)
      In this work we provide an effective method to prove the formal integrability of the resonant saddles. The method is based on the use of a blow-up and the resolution of a recurrence differential equation using induction. ...

    • A carotenogenic mini-pathway introduced into white corn does not affect development or agronomic performance 

      Zanga, Daniela; Capell Capell, Teresa; Slafer, Gustavo A.; Christou, Paul; Savin, Roxana (Nature, 2016)
      High-carotenoid corn (Carolight®) has been developed as a vehicle to deliver pro-vitamin A in the diet and thus address vitamin A deficiency in at-risk populations in developing countries. Like any other novel crop, the ...

    • A Case of Transatlantic Intertextuality: Edward Bulwer-Lytton and Edgar Allan Poe 

      Miquel Baldellou, Marta (Portuguese Association for Anglo-American Studies (APEAA), 2010)
      The American scholar Burton R. Pollin established literary connections between Edgar Allan Poe and the Victorian English writer Edward Bulwer-Lytton, tracing the influence the latter exerted over many of Poe’s tales ...

    • A Chebyshev criterion for Abelian integrals 

      Grau Montaña, Maite; Mañosas, Francesc; Villadelprat, Jordi (American Mathematical Society, 2010)
      We present a criterion that provides an easy sufficient condition in order that a collection of Abelian integrals has the Chebyshev property. This condition involves the functions in the integrand of the Abelian integrals ...

    • A cidade secreta: os espaços quotidianos dos jovens 

      Feixa, Carles (Fim de Século, 2003)