Browsing Articles publicats (Cirurgia) by Subject "Promoter methylation"
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hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells
(Spandidos Publications, 2011)Colorectal cancers exhibit a high telomerase activity, usually correlated with the hypermethylation of the promoter of its hTERT catalytic subunit. Although telomerase is not expressed in normal tissue, certain ...