Now showing items 1-4 of 4

    • EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer 

      Roman-Canal, Berta; Tarragona Foradada, Jordi; Moiola, Cristian P.; Gatius Calderó, Sònia; Bonnin, Sarah; Ruiz Miró, Maria; Sierra, José Enrique; Rufas, Maria; González, Esperanza; Porcel Pérez, José Manuel; Gil-Moreno, Antonio; Falcon-Perez, Juan M.; Ponomarenko, Julia; Matias-Guiu, Xavier; Colas, Eva (BioMed Central, 2019)
      Background: Colorectal cancer (CRC) is the third leading cause of cancer-related mortality worldwide. Current systematic methods for diagnosing have inherent limitations so development of a minimally-invasive diagnosis, ...
    • hTERT methylation is necessary but not sufficient for telomerase activity in colorectal cells 

      Valls i Bautista, Cristina; Bougel, Stéphanie; Piñol Felis, Carme; Viñas Salas, Joan; Benhattar, Jean (Spandidos Publications, 2011)
      Colorectal cancers exhibit a high telomerase activity, usually correlated with the hypermethylation of the promoter of its hTERT catalytic subunit. Although telomerase is not expressed in normal tissue, certain ...
    • Telomere length is a prognostic factor for overall survival in colorectal cancer 

      Valls i Bautista, Cristina; Piñol Felis, Carme; Reñé Espinet, Josep Maria; Buenestado Garcia, Juan; Viñas Salas, Joan (Wiley, 2011)
      Aim The aim of this study was to determine whether telomere length is an independent prognostic factor for the prevention and survival of colorectal cancer. Method Terminal restriction fragment (TRF) length was determined ...
    • Telomeric repeat factor 1 protein levels correlates with telomere length in colorectal cancer 

      Valls i Bautista, Cristina; Piñol Felis, Carme; Reñé Espinet, Josep Maria; Buenestado Garcia, Juan; Viñas Salas, Joan (Sociedad Española de Patología DigestivaArán Ediciones, 2012)
      Background: colorectal cancer is the third cancer cause of death in Spain. It is important to investigate new tumoral markers for early diagnosis, disease monitoring and prevention strategies. Telomeres protect the ...