Now showing items 1-9 of 9

    • A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants 

      Manunza, Arianna; Casellas, Joaquim; Quintanilla Aguado, Raquel; González-Prendes, Rayner; Pena i Subirà, Ramona Natacha; Tibau, Joan; Mercadé Carceller, Anna; Castelló, Anna; Aznarez, Nitdia; Hernández-Sánchez, Jules; Amills i Eras, Marcel (BioMed Central, 2014-09-10)
      Background: The genetic determinism of blood lipid concentrations, the main risk factor for atherosclerosis, is practically unknown in species other than human and mouse. Even in model organisms, little is known about how ...
    • About the existence of common determinants of gene expression in the porcine liver and skeletal muscle 

      González Prendes, Rayner; Mármol-Sánchez, Emilio; Quintanilla Aguado, Raquel; Castelló, Anna; Zidi, A.; Ramayo Caldas, Yuliaxis; Figueiredo Cardoso, Tainã; Manunza, Arianna; Cánovas, Angela; Amills i Eras, Marcel (BMC (part of Springer Nature), 2019-06-24)
      Background The comparison of expression QTL (eQTL) maps obtained in different tissues is an essential step to understand how gene expression is genetically regulated in a context-dependent manner. In the current work, we ...
    • Application of the microarray technology to the transcriptional analysis of muscle phenotypes in pigs 

      Pena i Subirà, Ramona Natacha; Quintanilla Aguado, Raquel; Manunza, Arianna; Gallardo García, David; Casellas, Joaquim; Amills i Eras, Marcel (Wiley, 2014-05-14)
      The transcriptome refers to the collection of all transcripts present in a cell. Gene expression has a very dynamic nature; it acts as a bridge between epigenetic marks, DNA sequence and proteins and changes to accommodate ...
    • Associations between pig adiponectin (ADIPOQ) genotype and serum lipid levels are modulated by age-specific modifiers 

      Castelló, Anna; Quintanilla Aguado, Raquel; Melo, C.; Gallardo García, David; Zidi, A.; Manunza, Arianna; Noguera Jiménez, José Luis; Tibau, Joan; Jordana i Vidal, Jordi; Pena i Subirà, Ramona Natacha; Amills i Eras, Marcel (American Society of Animal Science, 2014-12-15)
      The adiponectin (ADIPOQ) locus is a positional and functional candidate gene for 2 porcine chromosome 13 (SSC13) QTL influencing cholesterol (CHOL) and low-density lipoprotein (LDL) concentrations in 190-d-old pigs. By ...
    • Co-expression network analysis predicts a key role of microRNAs in the adaptation of the porcine skeletal muscle to nutrient supply 

      Mármol-Sánchez, Emilio; Ramayo Caldas, Yuliaxis; Quintanilla Aguado, Raquel; Figueiredo Cardoso, Tainã; González Prendes, Rayner; Tibau, Joan; Amills i Eras, Marcel (BMC (part of Springer Nature), 2020-01-17)
      Background The role of non-coding RNAs in the porcine muscle metabolism is poorly understood, with few studies investigating their expression patterns in response to nutrient supply. Therefore, we aimed to investigate the ...
    • Comparing the mRNA expression profile and the genetic determinism of intramuscular fat traits in the porcine gluteus medius and longissimus dorsi muscles 

      González-Prendes, Rayner; Quintanilla Aguado, Raquel; Mármol-Sánchez, Emilio; Pena i Subirà, Ramona Natacha; Ballester, Maria; Figueiredo Cardoso, Tainã; Manunza, Arianna; Casellas, Joaquim; Cánovas, Angela; Díaz, Isabel; Noguera Jiménez, José Luis; Castelló, Anna; Mercadé Carceller, Anna; Amills i Eras, Marcel (BMC (part of Springer Nature), 2019-03-04)
      Background: Intramuscular fat (IMF) content and composition have a strong impact on the nutritional and organoleptic properties of porcine meat. The goal of the current work was to compare the patterns of gene expression ...
    • Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits 

      González Prendes, Rayner; Quintanilla Aguado, Raquel; Cánovas, Angela; Manunza, Arianna; Figueiredo Cardoso, Tainã; Jordana i Vidal, Jordi; Noguera Jiménez, José Luis; Pena i Subirà, Ramona Natacha; Amills i Eras, Marcel (Nature, 2017)
      Meat quality traits have an increasing importance in the pig industry because of their strong impact on consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to map loci with potential ...
    • Muscle transcriptomic profiles in pigs with divergent phenotypes for fatness traits 

      Cánovas Tienda, Angela; Quintanilla Aguado, Raquel; Amills i Eras, Marcel; Pena i Subirà, Ramona Natacha (BioMed Central, 2010)
      BACKGROUND: Selection for increasing intramuscular fat content would definitively improve the palatability and juiciness of pig meat as well as the sensorial and organoleptic properties of cured products. However, evidences ...
    • Segregation of regulatory polymorphisms with effects on the gluteus medius transcriptome in a purebred pig population 

      Cánovas Tienda, Angela; Pena i Subirà, Ramona Natacha; Gallardo García, David; Ramírez Bellido, Óscar; Amills i Eras, Marcel; Quintanilla Aguado, Raquel (Public Library of Science (PLoS), 2012)
      Background: The main goal of the present study was to analyse the genetic architecture of mRNA expression in muscle, a tissue with an outmost economic importance for pig breeders. Previous studies have used F2 crosses to ...