Now showing items 1-4 of 4

    • Genetic architecture and major genes for backfat thickness in pig lines of diverse genetic backgrounds 

      Gozalo-Marcilla, Miguel; Buntjer, Jaap; Johnsson, Martin; Batista, Lorena; Diez, Federico; Werner, Christian R.; Chen, Ching-Yi; Gorjanc, Gregor; Mellanby, Richard J.; Hickey, John M.; Ros Freixedes, Roger (BMC, 2021-09-22)
      Background: Backfat thickness is an important carcass composition trait for pork production and is commonly included in swine breeding programmes. In this paper, we report the results of a large genome-wide association ...
    • Genetic variation in recombination rate in the pig 

      Johnsson, Martin; Whalen, Andrew; Ros Freixedes, Roger; Gorjanc, Gregor; Chen, Ching-Yi; Herring, William O.; Koning, Dirk‑Jan de; Hickey, John M. (BMC (part of Springer Nature), 2021-06-25)
      Background: Meiotic recombination results in the exchange of genetic material between homologous chromosomes. Recombination rate varies between different parts of the genome, between individuals, and is influenced by ...
    • Impact of index hopping and bias towards the reference allele on accuracy of genotype calls from low-coverage sequencing 

      Ros Freixedes, Roger; Battagin, Mara; Johnsson, Martin; Gorjanc, Gregor; Mileham, Alan J.; Rounsley, Steve D.; Hickey, John M. (BMC (part of Springer Nature), 2018-12-13)
      Background: Inherent sources of error and bias that affect the quality of sequence data include index hopping and bias towards the reference allele. The impact of these artefacts is likely greater for low-coverage data ...
    • Sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs 

      Johnsson, Martin; Ros Freixedes, Roger; Gorjanc, Gregor; Campbell, Matt A.; Naswa, Sudhir; Kelly, Kimberly; Lightner, Jonathan; Rounsley, Steve D.; Hickey, John M. (BMC (part of Springer Nature), 2018-12-20)
      Background: In this work, we investigated sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs. A functional CD163 protein is required for infection by porcine reproductive and respiratory ...