Now showing items 1-3 of 3

    • A method for the allocation of sequencing resources in genotyped livestock populations 

      Gonen, Serap; Ros Freixedes, Roger; Battagin, Mara; Gorjanc, Gregor; Hickey, John M. (BMC (part of Springer Nature), 2017-05-18)
      Background: This paper describes a method, called AlphaSeqOpt, for the allocation of sequencing resources in livestock populations with existing phased genomic data to maximise the ability to phase and impute sequenced ...
    • A strategy to exploit surrogate sire technology in livestock breeding programs 

      Gottardo, Paolo; Gorjanc, Gregor; Battagin, Mara; Gaynor, R.Chris; Jenko, Janez; Ros Freixedes, Roger; Whitelaw, C.Bruce A.; Mileham, Alan J.; Herring, William O.; Hickey, John M. (Genetics Society of America, 2019-01-09)
      In this work, we performed simulations to develop and test a strategy for exploiting surrogate sire technology in animal breeding programs. Surrogate sire technology allows the creation of males that lack their own germline ...
    • Impact of index hopping and bias towards the reference allele on accuracy of genotype calls from low-coverage sequencing 

      Ros Freixedes, Roger; Battagin, Mara; Johnsson, Martin; Gorjanc, Gregor; Mileham, Alan J.; Rounsley, Steve D.; Hickey, John M. (BMC (part of Springer Nature), 2018-12-13)
      Background: Inherent sources of error and bias that affect the quality of sequence data include index hopping and bias towards the reference allele. The impact of these artefacts is likely greater for low-coverage data ...