Browsing by Subject "DNA hypomethylation"

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    • Quantification of Unmethylated Alu (QUAlu): a tool to assess global hypomethylation in routine clinical samples 

      Buj, Raquel; Mallona, Izaskun; Díez Villanueva, Anna; Barrera, Víctor; Mauricio Puente, Dídac; Puig-Domingo, Manuel; Reverter, Jordi L.; Matias-Guiu, Xavier; Azuara, Daniel; Ramírez, Jose L.; Alonso, Sergio; Rosell, Rafael; Capellà, Gabriel; Perucho, Manuel; Robledo, Mercedes; Peinado, Miguel A.; Jordà, Mireia (Impact Journals, 2016)
      Hypomethylation of DNA is a hallmark of cancer and its analysis as tumor biomarker has been proposed, but its determination in clinical settings is hampered by lack of standardized methodologies. Here, we present QUAlu ...