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    • First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass 

      Wang, Guangliang; Rajpurohit, Surendra K.; Delaspre, Fabien; Walker, Steven L.; White, David T.; Ceasrine, Alexis; Kuruvilla, Rejji; Li, Ruo-jing; Shim, Joong S.; Liu, Jun O.; Parsons, Michael J.; Mumm, Jeff S. (eLife Sciences Publications, 2015-07-28)
      Whole-organism chemical screening can circumvent bottlenecks that impede drug discovery. However, in vivo screens have not attained throughput capacities possible with in vitro assays. We therefore developed a method ...