Now showing items 1-2 of 2

    • Notch signaling pathway is activated in motoneurons of spinal muscular atrophy 

      Cardona-Rossinyol, Andrea; Garcera, Ana; Torres-Benito, Laura; Soler i Tatché, Rosa Ma.; Tabares, Lucía; Lladó, Jerònia; Olmos, Gabriel; Caraballo-Miralles, Víctor (MDPI, 2013)
      Spinal muscular atrophy (SMA) is a neurodegenerative disease produced by low levels of Survival Motor Neuron (SMN) protein that affects alpha motoneurons in the spinal cord. Notch signaling is a cell-cell communication ...
    • Smn-deficiency increases the intrinsic excitability of motoneurons 

      Arumugam, Saravanan; Garcera, Ana; Soler i Tatché, Rosa Ma.; Tabares, Lucía (Frontiers Media, 2017)
      During development, motoneurons experience significant changes in their size and in the number and strength of connections that they receive, which requires adaptive changes in their passive and active electrical properties. ...