Browsing by Author "González, Luz María"
Now showing items 1-3 of 3
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A Custom Target Next-Generation Sequencing 70-Gene Panel and Replication Study to Identify Genetic Markers of Diabetic Kidney Disease
Mota Zamorano, Sonia; González, Luz María; Robles, Nicolás Roberto; Valdivielso Revilla, José Manuel; Cancho, Bárbara; López Gómez, Juan; Gervasini, Guillermo (MDPI, 2021)Diabetic kidney disease (DKD) has been pointed out as a prominent cause of chronic andend-stage renal disease (ESRD). There is a genetic predisposition to DKD, although clinically relevantloci are yet to be identified. We ... -
Genetic Variants in PGE2 Receptors Modulate the Risk of Nephrosclerosis and Clinical Outcomes in These Patients
González, Luz María; Robles, Nicolás Roberto; Mota Zamorano, Sonia; Valdivielso Revilla, José Manuel; López Gómez, Juan; Gervasini, Guillermo (MDPI, 2021)Prostaglandin E2 (PGE2) is a major actor mediating renal injury. We aimed to determine genetic variability in the genes coding for its receptors (PTGER1-4) and study associations with nephrosclerosis risk and clinical ... -
Genetics Variants in the Epoxygenase Pathway of Arachidonic Metabolism Are Associated with Eicosanoids Levels and the Risk of Diabetic Nephropathy
Mota Zamorano, Sonia; Robles, Nicolás Roberto; González, Luz María; Valdivielso Revilla, José Manuel; López Gómez, Juan; Cancho, Bárbara; García Pino, Guadalupe; Gervasini, Guillermo (MDPI, 2021)Genes in the epoxygenase pathway of arachidonic acid metabolism leading to vasoactive eicosanoids, mainly 20-hydroxyeicosatetraenoic (20-HETE) and epoxyeicosatrienoic (EETs) acids, have been related to glucose-induced renal ...