Agrotecnio aims to become a reference in Europe addressing all the key elements of the food production chain in an integrated way focusing on target crops and animals of commercial importance, rather than model systems. This later aspect sets our centre apart from other centers which focus on fundamental science and/or model plant and animal systems. As a result we should be able to address fundamental and important questions in the crop/animal of interest and results from our research will be directly and immediately applicable to our target organism. [Més informació]

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  • Plant Cells as Pharmaceutical Factories 

    Rischer, Heiko; Häkkinen, Suvi T.; Ritala, Anneli; Seppänen-Laakso, Tuulikki; Miralpeix i Anglada, Bruna; Capell Capell, Teresa; Christou, Paul; Oksman-Caldentey, Kirsi-Marja (Bentham Science Publishers, 2013)
    Molecules derived from plants make up a sizeable proportion of the drugs currently available on the market. These include a number of secondary metabolite compounds the monetary value of which is very high. New pharmaceuticals ...
  • Seeds as a production system for molecular pharming applications: status and prospects 

    Sabalza Gallués, Maite; Vamvaka, Evangelia; Christou, Paul; Capell Capell, Teresa (Bentham Science Publishers, 2013)
    The production of recombinant proteins in seeds is achieved by driving transgene expression using promoters and protein targeting sequences derived from genes encoding abundant seed storage proteins. This approach is ...
  • Floret development and grain setting differences between modern durum wheats under contrasting nitrogen availability 

    Ferrante, Ariel; Savin, Roxana; Slafer, Gustavo A. (Oxford University Press, 2013)
    Wheat yield depends on the number of grains per square metre, which in turn is related to the number of fertile florets at anthesis. The dynamics of floret generation/degeneration were studied in contrasting conditions of ...
  • Carbon uptake and water use in woodlands and forests in southern Australia during an extreme heat wave event in the “Angry Summer” of 2012/2013 

    van Gorsel, Eva; Wolf, Sebastian; James Cleverly, James; Isaac, Peter; Haverd, Vanessa; Ewenz, Cäcilia; Arndt, Stefan; Beringer, Jason; Resco de Dios, Víctor; Evans, Bradley J.; Griebel, Anne; Hutley, Lindsay B.; Keenan, Trevor; Kljun, Natascha; Macfarlane, Craig; Meyer, Wayne S.; McHugh, Ian; Pendall, Elise; Prober, Suzanne M.; Silberstein, Richard (Copernicus Publications, 2016)
    As a result of climate change warmer temperatures are projected through the 21st century and are already increasing above modelled predictions. Apart from increases in the mean, warm/hot temperature extremes are expected ...
  • Fast quantitative method for the analysis of carotenoids in transgenic maize 

    Rivera Vélez, Sol Maiam; Vilaró, Francisca; Zhu, Changfu; Bai, Chao; Farré Martinez, Gemma; Christou, Paul; Canela i Garayoa, Ramon (American Chemical Society, 2013)
    A fast method was developed to determine carotenoid content in transgenic maize seeds. The analysis was carried out using an ultrahigh-pressure liquid chromatograph coupled to a photodiode array detector and a mass ...
  • Fruiting efficiency in wheat: physiological aspects and geneticvariation among modern cultivars 

    Elía Martínez, Mónica; Savin, Roxana; Slafer, Gustavo A. (Elsevier, 2016)
    Efforts to enhance the yield of wheat require increases in the number of grains per m2 (GN) which depends on spike fertility, i.e. the number of fertile florets or grains per spike. Fruiting efficiency (FE), the number of ...
  • Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro 

    Vamvaka, Evangelia; Evans, A.; Ramessar, K.; Krumpe, L. R. H.; Shattock, R. J.; O’Keefe, B. R.; Christou, Paul; Capell Capell, Teresa (Springer Berlin Heidelberg, 2016)
    Cyanovirin-N (CV-N) is a lectin with potent antiviral activity that has been proposed as a component of microbicides for the prevention of infection with Human immunodeficiency virus (HIV). The production of protein-based ...
  • Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants 

    Ma, Julian K-C.; Drossard, Jürgen; Lewis, David; Altmann, Friedrich; Boyle, Julia; Christou, Paul; Cole, Tom; Dale, Philip; van Dolleweerd, Craig J.; Isitt, Valerie; Katinger, Dietmar; Lobedan, Martin; Mertens, Hubert; Paul, Mathew J.; Rademacher, Thomas; Sack, Markus; Hundleby, Penelope A. C.; Stiegler, Gabriela; Stoger, Eva; Twyman, Richard M.; Vcelar, Brigitta; Fischer, Rainer (Wiley, 2015)
    Although plant biotechnology has been widely investigated for the production of clinical-grade monoclonal antibodies, no antibody products derived from transgenic plants have yet been approved by pharmaceutical regulators ...
  • Forests synchronize their growth in contrasting Eurasian regions in response to climate warming 

    Shestakova, Tatiana A.; Gutiérrez, Emilia; Kirdyanov, Alexander V.; Julio Camarero, Jesús; Génova, Mar; Knorre, Anastasia A.; Linares, Juan Carlos; Resco de Dios, Víctor; Sánchez-Salguero, Raúl; Voltas Velasco, Jordi (National Academy of Sciences, 2016)
    Forests play a key role in the carbon balance of terrestrial ecosystems. One of the main uncertainties in global change predictions lies in how the spatiotemporal dynamics of forest productivity will be affected by climate ...
  • Positive biodiversity-productivity relationship predominant in global forests 

    Liang, Jingjing; Crowther, Thomas W.; Picard, Nicolas; Wiser, Susan; Zhou, Mo; Alberti, Giorgio; Schulze, Ernst-Detlef; McGuire, A. David; Bozzato, Fabio; Pretzsch, Hans; Miguel Magaña, Sergio de; Paquette, Alain; Hérault, Bruno; Scherer-Lorenzen, Michael; Barrett, Christopher B.; Glick, Henry B.; Hengeveld, Geerten M.; Nabuurs, Gert-Jan; Pfautsch, Sebastian; Viana, Helder; Vibrans, Alexander C.; Ammer, Christian; Schall, Peter; Verbyla, David; Tchebakova, Nadja; Fischer, Markus; Watson, James V.; Chen, Han Y. H.; Lei, Xiangdong; Schelhaas, Mart-Jan; Lu, Huicui; Gianelle, Damiano; Parfenova, Elena I.; Salas, Christian; Lee, Eungul; Lee, Boknam; Kim, Hyun Seok; Bruelheide, Helge; Coomes, David A.; Piotto, Daniel; Sunderland, Terry; Schmid, Bernhard; Gourlet-Fleury, Sylvie; Sonké, Bonaventure; Tavani, Rebecca; Zhu, Jun; Brandl, Susanne; Vayreda, Jordi; Kitahara, Fumiaki; Searle, Eric B.; Neldner, Victor J.; Ngugi, Michael R.; Baraloto, Christopher; Frizzera, Lorenzo; Bałazy, Radomir; Oleksyn, Jacek; Zawiła-Niedźwiecki, Tomasz; Bouriaud, Olivier; Bussotti, Filippo; Finér, Leena; Jaroszewicz, Bogdan; Jucker, Tommaso; Valladares, Fernando; Jagodzinski, Andrzej M.; Peri, Pablo L.; Gonmadje, Christelle; Marthy, William; O’Brien, Timothy; Martin, Emanuel H.; Marshall, Andrew R.; Rovero, Francesco; Bitariho, Robert; Niklaus, Pascal A.; Alvarez-Loayza, Patricia; Chamuya, Nurdin; Valencia, Renato; Mortier, Frédéric; Wortel, Verginia; Engone-Obiang, Nestor L.; Ferreira, Leandro V.; Odeke, David E.; Vasquez, Rodolfo M.; Lewis, Simon L.; Reich, Peter B. (American Association for the Advancement of Science, 2016)
    The biodiversity-productivity relationship (BPR) is foundational to our understanding of the global extinction crisis and its impacts on ecosystem functioning. Understanding BPR is critical for the accurate valuation and ...
  • Cloning and functional analysis of the promoters that upregulate carotenogenic gene expression during flower development in Gentiana lutea 

    Zhu, Changfu; Yang, Qingjie; Ni, Xiuzhen; Bai, Chao; Sheng, Yanmin; Shi, Lianxuan; Capell Capell, Teresa; Sandmann, Gerhard; Christou, Paul (Wiley, 2014)
    Over the last two decades, many carotenogenic genes have been cloned and used to generate metabolically engineered plants producing higher levels of carotenoids. However, comparatively little is known about the regulation ...
  • The expression of heterologous Fe (III) phytosiderophore transporter HvYS1 in rice increases Fe uptake, translocation and seed loading and excludes heavy metals by selective Fe transport 

    Banakar, Raviraj; Alvarez Fernández, Ána; Abadía, Javier; Capell Capell, Teresa; Christou, Paul (Wiley, 2016)
    Many metal transporters in plants are promiscuous, accommodating multiple divalent cations including some which are toxic to humans. Previous attempts to increase the iron (Fe) and zinc (Zn) content of rice endosperm by ...
  • Patterns of CRISPR/Cas9 activity in plants, animals and microbes 

    Bortesi, Luisa; Zhu, Changfu; Zischewski, Julia; Perez, Lucia; Bassié, Ludovic; Nadi, Riad; Forni, Giobbe; Boyd Lade, Sarah; Soto, Erika; Jin, Xin; Medina Piles, Vicente; Villorbina Noguera, Gemma; Muñoz Gràcia, Pilar; Farré Martinez, Gemma; Fischer, Rainer; Twyman, Richard M.; Capell Capell, Teresa; Christou, Paul; Schillberg, Stefan (Wiley, 2016)
    The CRISPR/Cas9 system and related RNA-guided endonucleases can introduce double-strand breaks (DSBs) at specific sites in the genome, allowing the generation of targeted mutations in one or more genes as well as more ...
  • Rice endosperm is cost-effective for the production of recombinant griffithsin with potent activity against HIV 

    Vamvaka, Evangelia; Arcalis, Elsa; Ramessar, Koreen; Evans, Abbey; O’Keefe, Barry R.; Shattock, Robin J.; Medina Piles, Vicente; Stöger, Eva; Christou, Paul; Capell Capell, Teresa (Wiley, 2016)
    Protein microbicides containing neutralizing antibodies and antiviral lectins may help to reduce the rate of infection with human immunodeficiency virus (HIV) if it is possible to manufacture the components in large ...
  • Circadian rhythms have significant effects on leaf-to-canopy scale gas exchange under field conditions 

    Resco de Dios, Víctor; Gessler, Arthur; Ferrio Díaz, Juan Pedro; Alday, Josu G.; Bahn, Michael; Castillo Díaz, Jorge del; Devidal, Sébastien; García Muñoz, Sonia; Kayler, Zachary; Landais, Damien; Martín Gómez, Paula; Milcu, Alexandru; Piel, Clément; Pirhofer Walzl, Karin; Ravel, Olivier; Salekin, Serajis; Tissue, David T.; Tjoelker, Mark G.; Voltas Velasco, Jordi; Roy, Jacques (BioMed Central, 2016)
    Molecular clocks drive oscillations in leaf photosynthesis, stomatal conductance, and other cell and leaf-level processes over ~24 h under controlled laboratory conditions. The influence of such circadian regulation over ...
  • Freedom-to-operate analysis of a transgenic multivitamin corn variety 

    Zanga, Daniela; Capell Capell, Teresa; Zhu, Changfu; Christou, Paul; Thangaraj, Harry (John Wiley & Sons, 2016)
    In this article, we explore the intellectual property (IP) landscape relevant to the production and commercialization of Carolight™, a transgenic multivitamin corn variety created on humanitarian grounds to address ...
  • Transdisciplinary weed research: new leverage on challenging weed problems? 

    Jordan, N.; Shut, M.; Graham, S; Barney, J. N.; Childs, D. Z.; Christensen, S; Cousens, R. D.; Davis, A. S.; Eizenberg, H.; Ervin, D. E.; Fernandez Quintanilla, C.; Harrison, L. J.; Harsch, M. A.; Haijting, S.; Liebman, M.; Loddo, D.; Mirsky, S. B.; Riemens, M.; Nieve, P.; Peltzer, D. A.; Renton, M.; Williams, M.; Recasens i Guinjuan, Jordi; Sonderskov, M. (Wiley, 2016)
    Transdisciplinary weed research (TWR) is a promising path to more effective management of challenging weed problems. We define TWR as an integrated process of inquiry and action that addresses complex weed problems in the ...
  • Effects of temperature, water activity and incubation time on fungal growth and aflatoxin B1 production by toxinogenic Aspergillus flavus isolates on sorghum seeds 

    Lahouar, Amani; Marín Sillué, Sònia; Saïd, Salem; Sanchís Almenar, Vicente; Crespo, Sempere, A. (Elsevier, 2016)
    Sorghum, which is consumed in Tunisia as human food, suffers from severe colonization by several toxigenic fungi and contamination by mycotoxins. The Tunisian climate is characterized by high temperature and humidity ...
  • Growth environment but not seed position on the parent plant affect seed germination of two Thlaspi arvense L. populations 

    Gesch, Russell W.; Royo-Esnal, Aritz; Edo-Tena, E.; Recasens i Guinjuan, Jordi; Isbell, T.A.; Forcella, Frank (Elsevier, 2016)
    Thlaspi arvense L is a common weed found in most temperate regions throughout the world that also shows excellent potential for domestication as an oilseed crop. The complexity of T. arvense seed dormancy presently makes ...
  • Meteorological conditions and site characteristics driving edible mushroom production in Pinus pinaster forests of Central Spain 

    Mengiste Taye, Zelalem; Martínez Peña, Fernando; Bonet Lledos, José Antonio; de Aragón, Juan Martínez; Miguel Magaña, Sergio de (Elsevier, 2016)
    Integrating fungal-based ecosystem services into forest management planning and policy-making requires quantitative knowledge of the yields of fungal sporocarps and their environmental drivers. The aim of this study was ...

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