El grup neix amb l'objectiu de poder englobar tota la recerca desenvolupada en l'Hospital sobre el malalt neurològic: malalties neurodeneratives, epilèpsia, esclerosi múltiple, cefalea i ictus. L'esperit del grup és poder estendre un pont al consolidat grup de Neurociències de l'Institut i d'aquesta forma poder formalitzar una recerca traslacional madura. [Més informació].

Recent Submissions

  • Estudio de intervención aleatorizado para evaluar la prevalencia de enfermedad ateromatosa y renal ocultas y su impacto en la morbimortalidad: Proyecto ILERVA 

    Betriu i Bars, M. Àngels; Farràs, Cristina; Abajo, María; Martínez Alonso, Montserrat; Arroyo, David; Barbé Illa, Ferran; Buti, Miquel; Lecube Torelló, Albert; Portero Otín, Manuel; Purroy Garcia, Francisco; Torres, Gerard; Valdivielso Revilla, José Manuel; Fernández i Giráldez, Elvira (Sociedad Española de Nefrología, 2016)
    Antecedentes y objetivos: La enfermedad renal crónica (ERC) y la ateromatosis son 2 enfermedades interrelacionadas que aumentan el riesgo de morbimortalidad cardiovascular. Los objetivos del proyecto ILERVAS son: 1) conocer ...
  • Metabolomics predicts neuroimaging characteristics of transient ischemic attack patients 

    Purroy Garcia, Francisco; Cambray Carner, Serafí; Mauri-Capdevila, Gerard; Jové Font, Mariona; Sanahuja Montesinos, Jordi; Farré, Joan; Benabdelhak Abbou, Ikram; Molina Seguin, Jessica; Colàs Campàs, Laura; Begué Gómez, Robert; Gil, M. Isabel; Pamplona Gras, Reinald; Portero Otín, Manuel (Elsevier, 2016)
    Background: Neuroimaging is essential for the diagnosis and prognosis of transient ischemic attack (TIA). The discovery of a plasmatic biomarker related to neuroimaging findings is of enormous interest because, despite ...
  • Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex 

    Cabré Cucó, Rosanna; Jové Font, Mariona; Naudí i Farré, Alba; Ayala Jové, Ma. Victoria (Maria Victoria); Piñol Ripoll, Gerard; Gil Villar, Maria P.; Dominguez Gonzalez, Mayelin; Obis Monné, Èlia; Berdun, Rebeca; Mota Martorell, Natalia; Portero Otín, Manuel; Ferrer, Isidre; Pamplona Gras, Reinald (Frontiers in Molecular Neurosciencie, 2016)
    Brain neurons offer diverse responses to stresses and detrimental factors during development and aging, and as a result of both neurodegenerative and neuropsychiatric disorders. This multiplicity of responses can be ascribed ...
  • Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism 

    Gonzalo Benito, Hugo; Brieva, Luis; Tatzber, Franz; Jové Font, Mariona; Cacabelos Barral, Daniel; Cassanyé, Anna; Lanau, Lucia; Boada Pallàs, Jordi; Serrano Casasola, José Carlos Enrique; González Mingot, Cristina; Hernández, Lourdes; Peralta, Sílvia; Pamplona Gras, Reinald; Portero Otín, Manuel (Wiley, 2012)
    Metabolomic and lipidomic analyses have been used for the profiling of neurodegenerative processes, both in targeted and untargeted approaches. In this work we have applied these techniques to the study of CSF samples of ...
  • Clinical evolution of elderly adults with ischemic stroke 

    Vena Martínez, Ana Belen; Cambray Carner, Serafí; Quilez Martínez, Alejandro; Molina Seguin, Jessica; Colàs Campàs, Laura; Sanahuja Montesinos, Jordi; González Mingot, Cristina; Purroy Garcia, Francisco; Benabdelhak Abbou, Ikram; Mauri-Capdevila, Gerard; Gil-Villar, María Pilar (Wiley, 2016)
  • Transdermal rotigotine improves sleep fragmentation in parkinson’s disease: results of the multicenter, prospective SLEEP-FRAM study 

    Pagonabarraga, Javier; Piñol Ripoll, Gerard; Cardozo, Adriana; Sanz, Pilar; Puente, Víctor; Otermín, Pilar; Legarda, Inés; Delgado, Tania; Serrano, Carmen; Balaguer, Ernest; Aguirregomozcorta, María; Álvarez, Ramiro; Kulisevsky, Jaime J. (Hindawi Publishing Corporation, 2015)
    Sleep disturbances occur frequently in patients with Parkinson’s disease (PD). The aim of this study was to investigate the effects of rotigotine on sleep fluctuations in a sample of PD patients with self-reported complaints ...
  • Metabolomics predicts stroke recurrence after transient ischemic attack 

    Jové Font, Mariona; Mauri-Capdevila, Gerard; Suárez-Luis, Idalmis; Cambray Carner, Serafí; Sanahuja Montesinos, Jordi; Quilez Martínez, Alejandro; Farré, Joan; Benabdelhak Abbou, Ikram; Pamplona Gras, Reinald; Portero Otín, Manuel; Purroy Garcia, Francisco (American Academy of Neurology, 2015)
    Objective: To discover, by using metabolomics, novel candidate biomarkers for stroke recurrence (SR) with a higher prediction power than present ones. Methods: Metabolomic analysis was performed by liquid chromatography ...
  • B-Type Natriuretic Peptides Help in Cardioembolic Stroke Diagnosis: Pooled Data Meta-Analysis. 

    Llombart Sebastià, Víctor; Antolin-Fontes, Albert; Bustamante Rangel, Alejandro; Giralt Casellas, Dolors; Rost, Natalia S.; Furie, Karen; Shibazaki, Kensaku; Biteker, Murat; Castillo, José; Rodríguez-Yáñez, Manuel; Fonseca, Ana Caterina; Watanabe, Tetsu; Purroy Garcia, Francisco; Zhixin, Wu; Etgen, Thorleif; Hosomi, Naohisa; Kerman, Scott Reza Jafarian; Sharma, Jagdish C.; Knauer, Carolin; Santamarina Pérez, Estevo; Giannakoulas, George; García Berrocoso, Teresa; Montaner Villalonga, Joan (American Heart Association, 2015-03-12)
    Background and Purpose. Determining the underlying cause of stroke is important to optimize secondary prevention treatment. Increased blood levels of natriuretic peptides (B-type natriuretic peptide/N-terminal pro-BNP ...
  • N-terminal pro-brain natriuretic peptide level determined at different times identifies transient ischaemic attack patients with atrial fibrillation 

    Purroy Garcia, Francisco; Suárez-Luis, Idalmis; Mauri-Capdevila, Gerard; Cambray Carner, Serafí; Farré, Joan; Sanahuja Montesinos, Jordi; Piñol Ripoll, Gerard; Quilez Martínez, Alejandro; González Mingot, Cristina; Begué Gómez, Robert; Gil, M. Isabel; Fernández i Giráldez, Elvira; Benabdelhak Abbou, Ikram (Wiley, 2014-06-25)
    BACKGROUND AND PURPOSE: The etiological classification of patients with transient ischaemic attack (TIA) is a difficult endeavor and the use of serum biomarkers could improve the diagnostic accuracy. The aim of this study ...
  • The incidence, prevalence, and mortality of stroke in France, Germany, Italy, Spain, the UK, and the US: a literature review 

    Zhang, Younan; Chapman, Ann-Marie; Plested, Melanie; Jackson, Daniel; Purroy Garcia, Francisco (Hindawi Publishing Corporation, 2012)
    Background. Although the burden of stroke in terms of mortality and disability has been well documented in previous years, data after 2000 are limited. Therefore, the aim of this paper was to identify the epidemiology of ...